FVB/N-Tg(E2F1-luc)1Ech/Kctt
| Status | Available to order |
| EMMA ID | EM:04994 |
| International strain name | FVB/N-Tg(E2F1-luc)1Ech/Kctt |
| Alternative name | Ef-luc |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(E2F1-luc)1Ech |
| Gene/Transgene symbol | Tg(E2F1-luc)1Ech |
Information from provider
| Provider | Lene Uhrbom |
| Provider affiliation | Department of Neuroscience, Uppsala University |
| Additional owner | Eric C Holland, Departments of Cancer Biology and Genetics, New York, NY , USA |
| Genetic information | Transgenic construct: pE2F1-luciferase. |
| Phenotypic information | Expression of firefly luciferase is regulated by the E2F1 promoter, allowing tumor cell development to be followed by luciferase imaging. |
| Breeding history | The founder mouse was crossed with FVB/N and subsequently intercrossed. |
| References |
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| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Karolinska Institutet, Stockholm, Sweden |
| Animals used for archiving | homozygous 0, wild-type FVB/N |
| Breeding at archiving centre | No breeding |
| Stage of embryos | 2-cell |
Literature references
- Dissecting tumor maintenance requirements using bioluminescence imaging of cell proliferation in a mouse glioma model.;Uhrbom Lene, Nerio Edward, Holland Eric C, ;2004;Nature medicine;10;1257-60; 15502845