B6.Cg-Tg(dlx5a-cre)1Mekk/Cnrm
| Status | Available to order |
| EMMA ID | EM:04892 |
| Citation information | RRID:IMSR_EM:04892 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6.Cg-Tg(dlx5a-cre)1Mekk/Cnrm |
| Alternative name | Dlx5/6-cre |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(dlx5a-cre)1Mekk |
| Gene/Transgene symbol | Tg(dlx5a-cre)1Mekk |
Information from provider
| Provider | Marc Ekker |
| Provider affiliation | Ottawa Hospital Research Institute |
| Genetic information | A Cre gene was placed under the control of the I56i and I56ii enhancer elements of zebrafish dlx5a and a 3.5kb genomic DNA fragment flanking the 5'-region of the zebrafish dlx6a open reading frame and containing the 5'-UTR. |
| Phenotypic information | No abnormal phenotype detected. |
| Breeding history | The line was backcrossed in C57BL/6 for 14 generations and it is currently maintained by siblings breedings. |
| References |
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| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Literature references
- The endocannabinoid system controls key epileptogenic circuits in the hippocampus.;Monory Krisztina, Massa Federico, Egertová Michaela, Eder Matthias, Blaudzun Heike, Westenbroek Ruth, Kelsch Wolfgang, Jacob Wolfgang, Marsch Rudolf, Ekker Marc, Long Jason, Rubenstein John L, Goebbels Sandra, Nave Klaus-Armin, During Matthew, Klugmann Matthias, Wölfel Barbara, Dodt Hans-Ulrich, Zieglgänsberger Walter, Wotjak Carsten T, Mackie Ken, Elphick Maurice R, Marsicano Giovanni, Lutz Beat, ;2006;Neuron;51;455-66; 16908411