| Status | Available to order |
| EMMA ID | EM:04785 |
| Citation information | RRID:IMSR_EM:04785 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6;129-Klf7tm1Rmz/Cnrm |
| Alternative name | Klf7 +/- |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Klf7tm1Rmz |
| Gene/Transgene symbol | Klf7 |
| Provider | Francesco Ramirez |
| Provider affiliation | Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine |
| Additional owner | Prof. Bruce Krueger, University of Maryland School of Medicine, Baltimore MD, U.S.A. |
| Genetic information | The targeting vector was designed to replace most of exon 1 with the phosphoglycerate kinase (PGK)-neo cassette flanked by loxP sites. |
| Phenotypic information | Klf7 +/- mice display no anatomical abnormalities and are fertile and viable. Klf7 knock-out mice die within 3 days after birth, displaying severely hypoplastic olfactory bulbs, and altered neuronal differentiation in the central nervous system. |
| Breeding history | The strain was inbred for 4 generations. It is currently bred using Klf7 +/- males and wild-type females. |
| References |
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| Homozygous fertile | no |
| Homozygous viable | no |
| Homozygous matings required | no |
| Immunocompromised | no |
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
