B6.Cg-Tg(tetO-Creb*)100Brco/Cnbc
| Status | Available to order |
| EMMA ID | EM:04664 |
| International strain name | B6.Cg-Tg(tetO-Creb*)100Brco/Cnbc |
| Alternative name | tetO-ACREB100 |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(tetO-Creb*)100Brco |
| Gene/Transgene symbol | Tg(tetO-Creb*)100Brco |
Information from provider
| Provider | Angel Barco |
| Provider affiliation | Servicio de Experimentación Animal, Instituto de Neurociencias de Alicante |
| Genetic information | Tetracycline regulated expression of the CREB inhibitor, A-CREB. Transgene intended to be used in bitransgenic lines after crossing with tTA or rtTA expressing mice. |
| Phenotypic information | After crossing with CamKIIa-tTA the bitransgenic line showed striatal specific expression. The addiction related phenotypes are described in Front Behav Neurosci. 2009;3:30. |
| Breeding history | Backcrossed to C57BL/6J for more than 15 generations. |
| References |
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| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | CNB-CSIC, Centro Nacional de Biotecnologia, Madrid, Spain |
| Animals used for archiving | heterozygous C57BL/6J, wild-type C57BL/6J |
| Stage of embryos | 8-cell |
Literature references
- Inhibition of cAMP responsive element binding protein in striatal neurons enhances approach and avoidance responses toward morphine--and morphine withdrawal-related cues.;Sanchis-Segura Carles, Jancic Dragana, Jimenez-Minchan Maria, Barco Angel, ;2009;Frontiers in behavioral neuroscience;3;30; 19826619