IMPC phenotypes (allele matching)
C57BL/6NTac-Urostm1a(EUCOMM)Wtsi/H
| Status | Available to order |
| EMMA ID | EM:04616 |
| Citation information | RRID:IMSR_EM:04616 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C57BL/6NTac-Urostm1a(EUCOMM)Wtsi/H |
| Alternative name | EPD0100_5_A01 |
| Strain type | Targeted Mutant Strains |
| Allele/Transgene symbol | Urostm1a(EUCOMM)Wtsi |
| Gene/Transgene symbol | Uros |
| Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
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Information from provider
| Provider | MRC, Medical Research Council |
| Provider affiliation | Mary Lyon Centre at MRC Harwell |
| Genetic information | This mouse line originates from EUCOMM ES clone EPD0100_5_A01. For further details on the construction of this clone see the page at the IMPC portal. |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References | None available |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
| Animals used for archiving | heterozygous C57BL/6NTac males |
| Breeding at archiving centre | Chimeras were mated to C57BL/6N Tac USA and maintained on this background thereafter. |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Congenital erythropoietic porphyria / Orphanet_79277
MGI phenotypes (gene matching)
- fragile skeleton / MGI
- abnormal erythropoiesis / MGI
- increased bone marrow cell number / MGI
- enlarged liver / MGI
- enlarged spleen / MGI
- thick skin / MGI
- skin photosensitivity / MGI
- thick epidermis / MGI
- abnormal dermal layer morphology / MGI
- mixed cellular infiltration to dermis / MGI
- hemolytic anemia / MGI
- acanthosis / MGI
- hepatic steatosis / MGI
- reticulocytosis / MGI
- anisocytosis / MGI
- poikilocytosis / MGI
- abnormal renal tubule morphology / MGI
- abnormal erythrocyte physiology / MGI
- increased porphyrin level / MGI
- abnormal proximal convoluted tubule morphology / MGI
- abnormal renal glomerulus morphology / MGI
- hematopoietic system phenotype / MGI
- abnormal circulating protein level / MGI
- abnormal skeleton morphology / MGI
- abnormal enzyme/coenzyme activity / MGI
- porphyria / MGI
- hypochromic microcytic anemia / MGI
- increased spleen red pulp amount / MGI
- increased spleen iron level / MGI
- abnormal dermis papillary layer morphology / MGI
- decreased birth body size / MGI
- embryonic lethality before implantation, complete penetrance / MGI
- preweaning lethality, complete penetrance / MGI
- erythruria / MGI
- erythrodontia / MGI