B6N.Cg-Tg(Gjc1/EGFP)L43Kwi/Cnrm
| Status | Available to order |
| EMMA ID | EM:04505 |
| Citation information | RRID:IMSR_EM:04505 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6N.Cg-Tg(Gjc1/EGFP)L43Kwi/Cnrm |
| Alternative name | Cx45eGFP |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(Gjc1/EGFP)L43Kwi |
| Gene/Transgene symbol | Tg(Gjc1/EGFP)L43Kwi |
Information from provider
| Provider | Klaus WILLECKE |
| Provider affiliation | Molekulargenetik, Institut fuer Genetik, Universitaet Bonn |
| Genetic information | The Cx45eGFP mouse line expresses a C-terminal fusion protein of connexin 45 (Gjc1) and eGFP, under control of the endogenous connexin 45 promoter using a bacterial artificial chromosome. |
| Phenotypic information | No obvious phenotypes could be detected. |
| Breeding history | The strain was backcrossed with C57BL/6N at least 5 times and is currently bred with C57BL/6N. |
| References |
|
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Literature references
- C-terminal tagging with eGFP yields new insights into expression of connexin45 but prevents rescue of embryonic lethal connexin45-deficient mice.;von Maltzahn Julia, Kreuzberg Maria M, Matern Gabi, Euwens Carsten, Höher Thorsten, Wörsdörfer Philipp, Willecke Klaus, ;2009;European journal of cell biology;88;481-94; 19473725