B6N.Cg-Tg(Gjc1/EGFP)L43Kwi/Cnrm
Status | Available to order |
EMMA ID | EM:04505 |
International strain name | B6N.Cg-Tg(Gjc1/EGFP)L43Kwi/Cnrm |
Alternative name | Cx45eGFP |
Strain type | Transgenic Strains |
Allele/Transgene symbol | Tg(Gjc1/EGFP)L43Kwi |
Gene/Transgene symbol | Tg(Gjc1/EGFP)L43Kwi |
Information from provider
Provider | Klaus WILLECKE |
Provider affiliation | Molekulargenetik, Institut fuer Genetik, Universitaet Bonn |
Genetic information | The Cx45eGFP mouse line expresses a C-terminal fusion protein of connexin 45 (Gjc1) and eGFP, under control of the endogenous connexin 45 promoter using a bacterial artificial chromosome. |
Phenotypic information | No obvious phenotypes could be detected. |
Breeding history | The strain was backcrossed with C57BL/6N at least 5 times and is currently bred with C57BL/6N. |
References |
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Homozygous fertile | not known |
Homozygous viable | not known |
Homozygous matings required | no |
Immunocompromised | no |
Information from EMMA
Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Literature references
- C-terminal tagging with eGFP yields new insights into expression of connexin45 but prevents rescue of embryonic lethal connexin45-deficient mice.;von Maltzahn Julia, Kreuzberg Maria M, Matern Gabi, Euwens Carsten, Höher Thorsten, Wörsdörfer Philipp, Willecke Klaus, ;2009;European journal of cell biology;88;481-94; 19473725
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