B6.FVB-1700016L21RikTg(Itgax-DTR/EGFP)57Lan/Orl
| Status | Available to order |
| EMMA ID | EM:00044 |
| International strain name | B6.FVB-1700016L21RikTg(Itgax-DTR/EGFP)57Lan/Orl |
| Alternative name | CD11C-DTR/GFP |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | 1700016L21RikTg(Itgax-HBEGF/EGFP)57Lan |
| Gene/Transgene symbol | 1700016L21Rik |
Information from provider
| Provider | Pierre AUCOUTURIER |
| Provider affiliation | INSERM U 712, Hôpital Saint Antoine - Maladies à prions et système immunitaire |
| Phenotypic information | CD11c-DTR mice have no phenotype, except that their dendritic cell compartment is uniquely sensitive to diphtheria toxin. |
| References |
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Information from EMMA
| Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
| Animals used for archiving | heterozygous C57BL/6J, wild-type C57BL/6J |
| Breeding at archiving centre | Transgenic males have been used for the freezing but it is not known if they are homozygous or heterozygous. The used females were C57BL/6J wild-type. Frozen embryos are at 2-cells or 4-8-cells stage. |
| Stage of embryos | 2-cell |
Literature references
- In vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens.;Jung Steffen, Unutmaz Derya, Wong Phillip, Sano Gen-Ichiro, De los Santos Kenia, Sparwasser Tim, Wu Shengji, Vuthoori Sri, Ko Kyung, Zavala Fidel, Pamer Eric G, Littman Dan R, Lang Richard A, ;2002;Immunity;17;211-20; 12196292
- Intestinal CD103+ dendritic cells are key players in the innate immune control of Cryptosporidium parvum infection in neonatal mice.;Lantier Louis, Lacroix-Lamandé Sonia, Potiron Laurent, Metton Coralie, Drouet Françoise, Guesdon William, Gnahoui-David Audrey, Le Vern Yves, Deriaud Edith, Fenis Aurore, Rabot Sylvie, Descamps Amandine, Werts Catherine, Laurent Fabrice, ;2013;PLoS pathogens;9;e1003801; 24367259
- Autophagy-dependent anticancer immune responses induced by chemotherapeutic agents in mice.;Michaud Mickaël, Martins Isabelle, Sukkurwala Abdul Qader, Adjemian Sandy, Ma Yuting, Pellegatti Patrizia, Shen Shensi, Kepp Oliver, Scoazec Marie, Mignot Grégoire, Rello-Varona Santiago, Tailler Maximilien, Menger Laurie, Vacchelli Erika, Galluzzi Lorenzo, Ghiringhelli François, di Virgilio Francesco, Zitvogel Laurence, Kroemer Guido, ;2011;Science (New York, N.Y.);334;1573-7; 22174255
- Dendritic cells control lymphocyte entry to lymph nodes through high endothelial venules.;Moussion Christine, Girard Jean-Philippe, ;2011;Nature;479;542-6; 22080953