B6.FVB-1700016L21RikTg(Itgax-DTR/EGFP)57Lan/Orl
| Status | Available to order |
| EMMA ID | EM:00044 |
| Citation information | RRID:IMSR_EM:00044 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6.FVB-1700016L21RikTg(Itgax-DTR/EGFP)57Lan/Orl |
| Alternative name | CD11C-DTR/GFP |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | 1700016L21RikTg(Itgax-HBEGF/EGFP)57Lan |
| Gene/Transgene symbol | 1700016L21Rik |
Information from provider
| Provider | Pierre AUCOUTURIER |
| Provider affiliation | INSERM U 712, Hôpital Saint Antoine - Maladies à prions et système immunitaire |
| Phenotypic information | CD11c-DTR mice have no phenotype, except that their dendritic cell compartment is uniquely sensitive to diphtheria toxin. |
| References |
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Information from EMMA
| Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
| Animals used for archiving | heterozygous C57BL/6J males, wild-type C57BL/6J females |
| Breeding at archiving centre | Transgenic males have been used for the freezing but it is not known if they are homozygous or heterozygous. The used females were C57BL/6J wild-type. Frozen embryos are at 2-cells or 4-8-cells stage. |
| Stage of embryos | 2-cell |
Literature references
- In vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens.;Jung Steffen, Unutmaz Derya, Wong Phillip, Sano Gen-Ichiro, De los Santos Kenia, Sparwasser Tim, Wu Shengji, Vuthoori Sri, Ko Kyung, Zavala Fidel, Pamer Eric G, Littman Dan R, Lang Richard A, ;2002;Immunity;17;211-20; 12196292
- Intestinal CD103+ dendritic cells are key players in the innate immune control of Cryptosporidium parvum infection in neonatal mice.;Lantier Louis, Lacroix-Lamandé Sonia, Potiron Laurent, Metton Coralie, Drouet Françoise, Guesdon William, Gnahoui-David Audrey, Le Vern Yves, Deriaud Edith, Fenis Aurore, Rabot Sylvie, Descamps Amandine, Werts Catherine, Laurent Fabrice, ;2013;PLoS pathogens;9;e1003801; 24367259
- Autophagy-dependent anticancer immune responses induced by chemotherapeutic agents in mice.;Michaud Mickaël, Martins Isabelle, Sukkurwala Abdul Qader, Adjemian Sandy, Ma Yuting, Pellegatti Patrizia, Shen Shensi, Kepp Oliver, Scoazec Marie, Mignot Grégoire, Rello-Varona Santiago, Tailler Maximilien, Menger Laurie, Vacchelli Erika, Galluzzi Lorenzo, Ghiringhelli François, di Virgilio Francesco, Zitvogel Laurence, Kroemer Guido, ;2011;Science (New York, N.Y.);334;1573-7; 22174255
- Dendritic cells control lymphocyte entry to lymph nodes through high endothelial venules.;Moussion Christine, Girard Jean-Philippe, ;2011;Nature;479;542-6; 22080953