C3H101H-Pax6Sey-H/H

Status

Available to order

EMMA IDEM:00437
International strain nameC3H101H-Pax6Sey-H/H
Alternative namePax6{Sey-H}
Strain typeInduced Mutant Strains : Radiation-induced
Allele/Transgene symbolPax6Sey-H
Gene/Transgene symbolPax6

Information from provider

ProviderJo Peters
Provider affiliationInstitute of Hearing Research, MRC (Medical Research Council)
Phenotypic informationMice carrying the Pax6Sey-H mutation have small eyes.
ReferencesNone available

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

IMPC phenotypes (gene matching)
  • abnormal craniofacial morphology / IMPC
  • microphthalmia / IMPC
  • anophthalmia / IMPC
  • abnormal liver morphology / IMPC
  • abnormal placenta morphology / IMPC
  • cleft palate / IMPC
  • hyperactivity / IMPC
  • corneal vascularization / IMPC
  • abnormal eye morphology / IMPC
  • cataract / IMPC
  • preweaning lethality, complete penetrance / IMPC
  • developmental dysplasia / IMPC
  • corneal opacity / IMPC
  • facial cleft / IMPC
  • abnormal placenta vasculature / IMPC
  • abnormal brain morphology / IMPC
  • small liver / IMPC
MGI phenotypes (allele matching)
  • small ears / MGI
  • lowered ear position / MGI
  • belly spot / MGI
  • decreased body size / MGI
  • microphthalmia / MGI
  • reduced female fertility / MGI
  • coloboma / MGI
  • embryonic lethality, complete penetrance / MGI
  • absent snout / MGI
  • anophthalmia / MGI
  • decreased embryo size / MGI
  • abnormal maxillary shelf morphology / MGI
  • abnormal face development / MGI
MGI phenotypes (gene matching)
  • small ears / MGI
  • lowered ear position / MGI
  • abnormal nasal bone morphology / MGI
  • belly spot / MGI
  • abnormal craniofacial morphology / MGI
  • short snout / MGI
  • absent snout / MGI
  • abnormal forebrain morphology / MGI
  • telencephalon hypoplasia / MGI
  • abnormal telencephalon morphology / MGI
  • abnormal cerebral cortex morphology / MGI
  • abnormal diencephalon morphology / MGI
  • abnormal cerebellum morphology / MGI
  • abnormal cerebellum vermis morphology / MGI
  • abnormal cerebellum external granule cell layer morphology / MGI
  • ectopic Purkinje cell / MGI
  • abnormal brain development / MGI
  • exencephaly / MGI
  • abnormal telencephalon development / MGI
  • decreased body length / MGI
  • decreased body size / MGI
  • abnormal eye development / MGI
  • abnormal lens induction / MGI
  • abnormal lens vesicle development / MGI
  • anophthalmia / MGI
  • microphthalmia / MGI
  • abnormal lens morphology / MGI
  • cataract / MGI
  • small lens / MGI
  • fused cornea and lens / MGI
  • abnormal cornea morphology / MGI
  • corneal opacity / MGI
  • abnormal pupil morphology / MGI
  • irregularly shaped pupil / MGI
  • abnormal iris morphology / MGI
  • abnormal retina morphology / MGI
  • abnormal optic nerve morphology / MGI
  • abnormal lacrimal gland morphology / MGI
  • decreased embryo size / MGI
  • reduced female fertility / MGI
  • abnormal pancreas morphology / MGI
  • respiratory failure / MGI
  • blindness / MGI
  • neoplasm / MGI
  • increased tumor incidence / MGI
  • premature death / MGI
  • abnormal eye morphology / MGI
  • abnormal craniofacial bone morphology / MGI
  • no abnormal phenotype detected / MGI
  • abnormal brain commissure morphology / MGI
  • abnormal CNS synaptic transmission / MGI
  • abnormal nose morphology / MGI
  • abnormal nasal cavity morphology / MGI
  • increased intestinal adenoma incidence / MGI
  • mydriasis / MGI
  • abnormal eye size / MGI
  • abnormal vitreous body morphology / MGI
  • abnormal lens fiber morphology / MGI
  • white spotting / MGI
  • aphakia / MGI
  • abnormal cornea anterior stroma morphology / MGI
  • abnormal respiratory system development / MGI
  • abnormal forebrain development / MGI
  • abnormal lens epithelium morphology / MGI
  • abnormal optic vesicle formation / MGI
  • absent olfactory bulb / MGI
  • nervous system phenotype / MGI
  • abnormal synaptic transmission / MGI
  • abnormal retinal photoreceptor layer morphology / MGI
  • abnormal facial morphology / MGI
  • abnormal submandibular gland morphology / MGI
  • abnormal craniofacial development / MGI
  • abnormal hormone level / MGI
  • abnormal cerebellar granule cell morphology / MGI
  • abnormal spinal cord interneuron morphology / MGI
  • abnormal pallium development / MGI
  • decreased fetal size / MGI
  • abnormal iridocorneal angle / MGI
  • abnormal optic cup morphology / MGI
  • abnormal embryonic/fetal subventricular zone morphology / MGI
  • abnormal postnatal subventricular zone morphology / MGI
  • abnormal maxillary shelf morphology / MGI
  • abnormal nasal capsule morphology / MGI
  • increased susceptibility to induced pancreatitis / MGI
  • abnormal neuron physiology / MGI
  • abnormal neuronal precursor proliferation / MGI
  • decreased circulating growth hormone level / MGI
  • decreased adrenocorticotropin level / MGI
  • decreased eye pigmentation / MGI
  • abnormal anterior eye segment morphology / MGI
  • abnormal retinal pigment epithelium morphology / MGI
  • abnormal eye anterior chamber morphology / MGI
  • abnormal olfactory nerve morphology / MGI
  • abnormal retinal ganglion layer morphology / MGI
  • aniridia / MGI
  • coloboma / MGI
  • impaired glucose tolerance / MGI
  • abnormal corneal stroma morphology / MGI
  • abnormal corneal endothelium morphology / MGI
  • renal/urinary system phenotype / MGI
  • craniofacial phenotype / MGI
  • vision/eye phenotype / MGI
  • hypopigmentation / MGI
  • corneal vascularization / MGI
  • abnormal lens development / MGI
  • abnormal corneal epithelium morphology / MGI
  • iris hypoplasia / MGI
  • thin cerebral cortex / MGI
  • absent nasal placodes / MGI
  • abnormal cortical plate morphology / MGI
  • thin cortical plate / MGI
  • abnormal cortical ventricular zone morphology / MGI
  • abnormal Bowman membrane / MGI
  • abnormal olfactory epithelium morphology / MGI
  • absent pancreatic beta cells / MGI
  • absent pancreatic alpha cells / MGI
  • disorganized pancreatic islets / MGI
  • delayed eyelid fusion / MGI
  • submandibular gland hypoplasia / MGI
  • abnormal pretectal region morphology / MGI
  • decreased birth body size / MGI
  • absent lens vesicle / MGI
  • abnormal retinal development / MGI
  • eye opacity / MGI
  • abnormal lateral nasal prominence morphology / MGI
  • abnormal medial nasal prominence morphology / MGI
  • abnormal neuron differentiation / MGI
  • anterior polar cataracts / MGI
  • increased alimentary system tumor incidence / MGI
  • increased stomach tumor incidence / MGI
  • corneal-lenticular stalk / MGI
  • postnatal lethality, complete penetrance / MGI
  • postnatal lethality, incomplete penetrance / MGI
  • neonatal lethality, complete penetrance / MGI
  • neonatal lethality, incomplete penetrance / MGI
  • perinatal lethality, complete penetrance / MGI
  • perinatal lethality, incomplete penetrance / MGI
  • prenatal lethality, complete penetrance / MGI
  • embryonic lethality, complete penetrance / MGI
  • embryonic lethality between implantation and somite formation, complete penetrance / MGI
  • prenatal lethality, incomplete penetrance / MGI
  • embryonic lethality, incomplete penetrance / MGI
  • embryonic lethality before implantation, incomplete penetrance / MGI
  • anterior iris synechia / MGI
  • abnormal endocrine pancreas development / MGI
  • abnormal optic placode morphology / MGI
  • absent external nares / MGI
  • small thalamus / MGI
  • decreased corneal epithelium thickness / MGI
  • absent nasal pit / MGI
  • abnormal face development / MGI

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Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*
  • Tissue - Types of tissue, service fee and delivery time available upon request

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

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