| Status | Available to order |
| EMMA ID | EM:04329 |
| Citation information | RRID:IMSR_EM:04329 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6.Cg-Jmjd6tm1.1Gbf/Ieg |
| Alternative name | C57Bl/6J-Jmjd6 tm1.1 Gbf |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Jmjd6tm1.1Gbf |
| Gene/Transgene symbol | Jmjd6 |
| Provider | Andreas Lengeling |
| Provider affiliation | Tierhaus TEE, Helmholtz Centre for Infection Research |
| Genetic information | Intragenic deletion of exon 1 and 2. This allele was created by removing the floxed neomycin cassette from Jmjd6tm1Gbf mice by crossing them to a CMV cre deleter line. |
| Phenotypic information | Mice homozygous for disruption in this gene show neonatal lethality. Abnormalities are observed in the nervous, cardiovascular, digestive, renal, hematopoietic, and immune systems. |
| Breeding history | The mutation was generated in Bruce 4 ES cells. Germline chimeras were bred to C57BL/6J mice to establish a breeding colony. Since then the strain has been maintained by brother x sister matings (>15 generations). |
| References |
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| Homozygous fertile | no |
| Homozygous viable | no |
| Homozygous matings required | no |
| Immunocompromised | no |
| Archiving centre | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany |
| Animals used for archiving | heterozygous C57BL/6J males, wild-type C57BL/6J females |
| Stage of embryos | 2-cell |
