| Status | Available to order |
| EMMA ID | EM:04329 |
| International strain name | B6.Cg-Jmjd6tm1.1Gbf/Ieg |
| Alternative name | C57Bl/6J-Jmjd6 tm1.1 Gbf |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Jmjd6tm1.1Gbf |
| Gene/Transgene symbol | Jmjd6 |
| Provider | Andreas Lengeling |
| Provider affiliation | Tierhaus TEE, Helmholtz Centre for Infection Research |
| Genetic information | Intragenic deletion of exon 1 and 2. This allele was created by removing the floxed neomycin cassette from Jmjd6tm1Gbf mice by crossing them to a CMV cre deleter line. |
| Phenotypic information | Mice homozygous for disruption in this gene show neonatal lethality. Abnormalities are observed in the nervous, cardiovascular, digestive, renal, hematopoietic, and immune systems. |
| Breeding history | The mutation was generated in Bruce 4 ES cells. Germline chimeras were bred to C57BL/6J mice to establish a breeding colony. Since then the strain has been maintained by brother x sister matings (>15 generations). |
| References |
|
| Homozygous fertile | no |
| Homozygous viable | no |
| Homozygous matings required | no |
| Immunocompromised | no |
| Archiving centre | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany |
| Animals used for archiving | heterozygous C57BL/6J, wild-type C57BL/6J |
| Stage of embryos | 2-cell |
