B6;129-Bsgtm1.1Kuv/Orl

Status

Available to order

EMMA IDEM:04318
International strain nameB6;129-Bsgtm1.1Kuv/Orl
Alternative nameB6.129Sv/Pas-Emmprin_tm
Strain typeTargeted Mutant Strains : Knock-out
Allele/Transgene symbolBsgtm1.1Kuv
Gene/Transgene symbolBsg

Information from provider

ProviderPhilip ROSENSTIEL
Provider affiliationIKMB, University of Kiel
Genetic informationDeletion of most of basigin (CD147 or EMMPRIN) protein by insertion of two loxP sites flanking exons 2 to 7 and breeding with cre-deleter. Details available upon request.
Phenotypic informationNot known.
Breeding historyBackcrossed to C57BL/6 for less than 5 generations.
ReferencesNone available
Homozygous fertilenot known
Homozygous viablenot known
Homozygous matings requirednot known
Immunocompromisednot known

Information from EMMA

Archiving centreInstitut de Transgenose, INTRAGENE, Orléans, France
Animals used for archivingheterozygous , wild-type C57BL/6J

Disease and phenotype information

MGI phenotypes (gene matching)
  • abnormal liver morphology / MGI
  • small liver / MGI
  • abnormal spermatogenesis / MGI
  • decreased body weight / MGI
  • interstitial pneumonia / MGI
  • male infertility / MGI
  • female infertility / MGI
  • respiratory distress / MGI
  • azoospermia / MGI
  • arrest of male meiosis / MGI
  • postnatal lethality, incomplete penetrance / MGI
  • embryonic lethality at implantation, incomplete penetrance / MGI

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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