FVB/N-Tg(Gfap-cre)2Brn/Cnrm

Status	Available to order
EMMA ID	EM:00411
International strain name	FVB/N-Tg(Gfap-cre)2Brn/Cnrm
Alternative name	Gcre or Tg(GFAP-Cre)2Brn
Strain type	Transgenic Strains
Allele/Transgene symbol	Tg(Gfap-cre)2Brn
Gene/Transgene symbol	Tg(Gfap-cre)2Brn

Information from provider

Provider	Anton Berns
Provider affiliation	Research - Animal Facility, The Netherlands Cancer Institute
Genetic information	2 kb of Gfap 5' flanking sequences (promoter), 89 residues of Gfap exon 1, 0.2 kb of SV40 DNA with splice signals, 1 kb cre recombinase-coding region and 0.2 kb of SV40 DNA with a polyA followed by the rest of the Gfap gene.
Phenotypic information	Gfap-cre (Gcre) mice show no obvious phenotype.
References	Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of Rb in the external granular layer cells of the cerebellum.;Marino S, Vooijs M, van Der Gulden H, Jonkers J, Berns A, ;2000;Genes & development;14;994-1004; 10783170

Information from EMMA

Archiving centre	CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy

Literature references

Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of Rb in the external granular layer cells of the cerebellum.;Marino S, Vooijs M, van Der Gulden H, Jonkers J, Berns A, ;2000;Genes & development;14;994-1004; 10783170

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Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740^*
Rederivation of mice from frozen stock, delivery time available upon request . €3880^*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

^* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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