FVB/N-Tg(Gfap-cre)2Brn/Cnrm
| Status | Available to order |
| EMMA ID | EM:00411 |
| Citation information | RRID:IMSR_EM:00411 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | FVB/N-Tg(Gfap-cre)2Brn/Cnrm |
| Alternative name | Gcre or Tg(GFAP-Cre)2Brn |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(Gfap-cre)2Brn |
| Gene/Transgene symbol | Tg(Gfap-cre)2Brn |
Information from provider
| Provider | Anton Berns |
| Provider affiliation | Research - Animal Facility, The Netherlands Cancer Institute |
| Genetic information | 2 kb of Gfap 5' flanking sequences (promoter), 89 residues of Gfap exon 1, 0.2 kb of SV40 DNA with splice signals, 1 kb cre recombinase-coding region and 0.2 kb of SV40 DNA with a polyA followed by the rest of the Gfap gene. |
| Phenotypic information | Gfap-cre (Gcre) mice show no obvious phenotype. |
| References |
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Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Literature references
- Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of Rb in the external granular layer cells of the cerebellum.;Marino S, Vooijs M, van Der Gulden H, Jonkers J, Berns A, ;2000;Genes & development;14;994-1004; 10783170