B6.Cg-Tg(Cebpb-rtTA2S*S2)1Bjd/Cnrm
| Status | Available to order |
| EMMA ID | EM:00404 |
| International strain name | B6.Cg-Tg(Cebpb-rtTA2S*S2)1Bjd/Cnrm |
| Alternative name | rTALAP-1 |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(Cebpb-rtTA2S*S2)1Bjd |
| Gene/Transgene symbol | Tg(Cebpb-rtTA2S*S2)1Bjd |
Information from provider
| Provider | Hermann Bujard |
| Provider affiliation | Zentrum für Molekulare Biologie Heidelberg- ZMBH |
| Genetic information | Transgenic rTALAP-1 mice contain a transcription unit consisting of the liver-enriched activating protein (LAP or Cebpb) promoter region which extends to nt 2800, and a synthetic gene encoding the rtTA2S-S2 transactivator variant (Urlinger et al., Proc Natl Acad Sci USA ,2000), followed by the beta-globin intron/poly(A) sequence. |
| Phenotypic information | Expression of the rtTA2S-S2 transactivator variant (Urlinger et al., Proc Natl Acad Sci USA, 2000), followed by the beta-globin intron/poly(A) sequence. |
| References |
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Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Literature references
- Stringent doxycycline dependent control of CRE recombinase in vivo.;Schönig Kai, Schwenk Frieder, Rajewsky Klaus, Bujard Hermann, ;2002;Nucleic acids research;30;e134; 12466566
- Use of the tetracycline system for inducible protein synthesis in the kidney.;Gallagher Anna Rachel, Schönig Kai, Brown Nelson, Bujard Hermann, Witzgall Ralph, ;2003;Journal of the American Society of Nephrology : JASN;14;2042-51; 12874458
- Exploring the sequence space for tetracycline-dependent transcriptional activators: novel mutations yield expanded range and sensitivity.;Urlinger S, Baron U, Thellmann M, Hasan M T, Bujard H, Hillen W, ;2000;Proceedings of the National Academy of Sciences of the United States of America;97;7963-8; 10859354
- Pathogenetic mechanisms of amyloid A amyloidosis.;Simons J Paul, Al-Shawi Raya, Ellmerich Stephan, Speck Ivana, Aslam Samrina, Hutchinson Winston L, Mangione Palma P, Disterer Petra, Gilbertson Janet A, Hunt Toby, Millar David J, Minogue Shane, Bodin Karl, Pepys Mark B, Hawkins Philip N, ;2013;Proceedings of the National Academy of Sciences of the United States of America;110;16115-20; 23959890
- Tissue-specific expression of ferritin H regulates cellular iron homoeostasis in vivo.;Wilkinson John, Di Xiumin, Schönig Kai, Buss Joan L, Kock Nancy D, Cline J Mark, Saunders Thomas L, Bujard Hermann, Torti Suzy V, Torti Frank M, ;2006;The Biochemical journal;395;501-7; 16448386