IMPC phenotypes (gene matching)
- increased circulating triglyceride level / IMPC
STOCK Tmc1dn/WtsiH
| Status | Available to order |
| EMMA ID | EM:00386 |
| Citation information | RRID:IMSR_EM:00386 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | STOCK Tmc1dn/WtsiH |
| Alternative name | Dn |
| Strain type | Spontaneous |
| Allele/Transgene symbol | Tmc1dn |
| Gene/Transgene symbol | Tmc1 |
Information from provider
| Provider | Karen Steel |
| Provider affiliation | Wellcome Trust Sanger Institute |
| Genetic information | The mutation is a 1656 bp deletion including exon 14 and flanking intronic sequences. |
| Phenotypic information | Mice homozygous for this mutation are deaf and show no Preyer reflex. Heterozygotes and wild-types are indistinguishable. |
| References | None available |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
MGI allele-associated human disease models
MGI phenotypes (allele matching)
- hearing/vestibular/ear phenotype / MGI
- organ of Corti degeneration / MGI
- abnormal stria vascularis morphology / MGI
- abnormal hearing physiology / MGI
- deafness / MGI
- abnormal motor capabilities/coordination/movement / MGI
- abnormal ear morphology / MGI
- cochlear ganglion degeneration / MGI
- abnormal otolith morphology / MGI
- abnormal tectorial membrane morphology / MGI
- abnormal scala media morphology / MGI
- nervous system phenotype / MGI
- vestibular saccular macula degeneration / MGI
- Deiters cell degeneration / MGI
- head tossing / MGI
MGI phenotypes (gene matching)
- cochlear degeneration / MGI
- organ of Corti degeneration / MGI
- abnormal stria vascularis morphology / MGI
- abnormal gait / MGI
- abnormal hearing physiology / MGI
- deafness / MGI
- abnormal motor capabilities/coordination/movement / MGI
- abnormal ear morphology / MGI
- cochlear ganglion degeneration / MGI
- abnormal otolith morphology / MGI
- abnormal tectorial membrane morphology / MGI
- abnormal scala media morphology / MGI
- nervous system phenotype / MGI
- abnormal organ of Corti supporting cell morphology / MGI
- abnormal Deiters cell morphology / MGI
- vestibular saccular macula degeneration / MGI
- cochlear hair cell degeneration / MGI
- cochlear inner hair cell degeneration / MGI
- cochlear outer hair cell degeneration / MGI
- abnormal hair cell mechanoelectric transduction / MGI
- abnormal outer hair cell stereociliary bundle morphology / MGI
- Deiters cell degeneration / MGI
- head tossing / MGI
- hearing/vestibular/ear phenotype / MGI
- behavior/neurological phenotype / MGI
- impaired hearing / MGI
- increased or absent threshold for auditory brainstem response / MGI