IMPC phenotypes (gene matching)
- increased circulating triglyceride level / IMPC
STOCK Tmc1dn/WtsiH
| Status | Available to order |
| EMMA ID | EM:00386 |
| International strain name | STOCK Tmc1dn/WtsiH |
| Alternative name | Dn |
| Strain type | Spontaneous |
| Allele/Transgene symbol | Tmc1dn |
| Gene/Transgene symbol | Tmc1 |
Information from provider
| Provider | Karen Steel |
| Provider affiliation | Wellcome Trust Sanger Institute |
| Genetic information | The mutation is a 1656 bp deletion including exon 14 and flanking intronic sequences. |
| Phenotypic information | Mice homozygous for this mutation are deaf and show no Preyer reflex. Heterozygotes and wild-types are indistinguishable. |
| References | None available |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
MGI allele-associated human disease models
MGI phenotypes (allele matching)
- hearing/vestibular/ear phenotype / MGI
- organ of Corti degeneration / MGI
- abnormal stria vascularis morphology / MGI
- abnormal hearing physiology / MGI
- deafness / MGI
- abnormal motor capabilities/coordination/movement / MGI
- abnormal ear morphology / MGI
- cochlear ganglion degeneration / MGI
- abnormal otolith morphology / MGI
- abnormal tectorial membrane morphology / MGI
- abnormal scala media morphology / MGI
- nervous system phenotype / MGI
- vestibular saccular macula degeneration / MGI
- Deiters cell degeneration / MGI
- head tossing / MGI
MGI phenotypes (gene matching)
- cochlear degeneration / MGI
- organ of Corti degeneration / MGI
- abnormal stria vascularis morphology / MGI
- abnormal gait / MGI
- abnormal hearing physiology / MGI
- deafness / MGI
- abnormal motor capabilities/coordination/movement / MGI
- abnormal ear morphology / MGI
- cochlear ganglion degeneration / MGI
- abnormal otolith morphology / MGI
- abnormal tectorial membrane morphology / MGI
- abnormal scala media morphology / MGI
- nervous system phenotype / MGI
- abnormal organ of Corti supporting cell morphology / MGI
- abnormal Deiters cell morphology / MGI
- vestibular saccular macula degeneration / MGI
- cochlear hair cell degeneration / MGI
- cochlear inner hair cell degeneration / MGI
- cochlear outer hair cell degeneration / MGI
- abnormal hair cell mechanoelectric transduction / MGI
- abnormal outer hair cell stereociliary bundle morphology / MGI
- Deiters cell degeneration / MGI
- head tossing / MGI
- hearing/vestibular/ear phenotype / MGI
- behavior/neurological phenotype / MGI
- impaired hearing / MGI
- increased or absent threshold for auditory brainstem response / MGI