MGI phenotypes (allele matching)
B10.BR-H2k/SnOrl
| Status | Available to order |
| EMMA ID | EM:00034 |
| Citation information | RRID:IMSR_EM:00034 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B10.BR-H2k/SnOrl |
| Alternative name | C57BL/10BR |
| Strain type | Other |
| Allele/Transgene symbol | H2k |
| Gene/Transgene symbol | H2 |
Information from provider
| Provider | CDTA unknown |
| Provider affiliation | CNRS-Orleans |
| Phenotypic information | Sub-strain of C57BL/10, congenic for H2-K haplotype. Genetic background of C57BL/10 with introduction of a different allele (H2-K) derived from C57BR/Orl strain |
| References |
|
Information from EMMA
| Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
Disease and phenotype information
MGI phenotypes (gene matching)
- decreased hematocrit / MGI
- abnormal liver physiology / MGI
- abnormal T cell differentiation / MGI
- increased susceptibility to bacterial infection / MGI
- abnormal immunoglobulin level / MGI
- increased IgM level / MGI
- abnormal cytokine secretion / MGI
- thyroid inflammation / MGI
- increased autoantibody level / MGI
- insulitis / MGI
- increased susceptibility to autoimmune diabetes / MGI
- decreased susceptibility to autoimmune diabetes / MGI
- decreased susceptibility to parasitic infection / MGI
- immune system phenotype / MGI
- periinsulitis / MGI
- abnormal T cell number / MGI
- decreased CD4-positive, alpha beta T cell number / MGI
- increased CD8-positive, alpha-beta T cell number / MGI
- decreased IgG1 level / MGI
- decreased IgG2a level / MGI
- increased physiological sensitivity to xenobiotic / MGI
- decreased physiological sensitivity to xenobiotic / MGI
- increased sensitivity to induced morbidity/mortality / MGI
Literature references
- Induction of resistance to antibody-mediated cytotoxicity. H-2, Ia, and Ig antigens are independent entities in the membrane of mouse lymphocytes.;Hauptfeld V, Hauptfeld M, Klein J, ;1975;The Journal of experimental medicine;141;1047-56; 47892