B6;129S7-Dp(16Dgcr14-Sept5)3Bld/Cnrm
| Status | Available to order |
| EMMA ID | EM:03114 |
| Citation information | RRID:IMSR_EM:03114 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6;129S7-Dp(16Dgcr14-Sept5)3Bld/Cnrm |
| Alternative name | Dp(16)3 (alias 340cdcdup) |
| Strain type | Targeted Mutant Strains : Other targeted |
| Allele/Transgene symbol | Dp(16Dgcr14-Sept5)3Bld |
| Gene/Transgene symbol | Dp(16Dgcr14-Sept5)3Bld |
Information from provider
| Provider | Antonio BALDINI |
| Provider affiliation | institute of biosciences and technologies, Texas A&M health science center |
| Genetic information | A proximal loxP site replaced part of exon 4 of gene Es2el (Dgcr14). A distal loxP site replaced exons 2-4 of gene Cdcrel1 (Sept5). Cre-mediated recombination was used to generate a tandem duplication of the region spanning Es2el - Cdcrel1 on MMU16. |
| Phenotypic information | No known phenotype in heterozygous or homozygous mutants. |
| Breeding history | Maintained on mixed C57BL/6; 129/SvEv |
| References |
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| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Literature references
- Tbx1 haploinsufficieny in the DiGeorge syndrome region causes aortic arch defects in mice.;Lindsay E A, Vitelli F, Su H, Morishima M, Huynh T, Pramparo T, Jurecic V, Ogunrinu G, Sutherland H F, Scambler P J, Bradley A, Baldini A, ;2001;Nature;410;97-101; 11242049