B6.Cg-Tg(tetO-Gja1,-EGFP)L11Kwi/Cnrm

Status

Available to order

EMMA IDEM:02594
International strain nameB6.Cg-Tg(tetO-Gja1,-EGFP)L11Kwi/Cnrm
Alternative nameCx43tetOeGFP
Strain typeTransgenic Strains
Allele/Transgene symbolTg(tetO-Gja1,-EGFP)L11Kwi
Gene/Transgene symbolTg(tetO-Gja1,-EGFP)L11Kwi

Information from provider

ProviderKlaus WILLECKE
Provider affiliationMolekulargenetik, Institut fuer Genetik, Universitaet Bonn
Genetic informationThe transgene contains a bidirectional tetracycline responsive promoter flanked on one side by the Cx43 (Gja1) coding region and on the other side by the eGFP coding region. Expression of a tetracycline transactivator leads to the expression of Cx43 and eGFP, respectively.
Phenotypic informationNo obvious phenotype could be detected.
Breeding historyFounder animals were backcrossed to C57BL/6 more than five times.
References
  • Engraftment of connexin 43-expressing cells prevents post-infarct arrhythmia.;Roell Wilhelm, Lewalter Thorsten, Sasse Philipp, Tallini Yvonne N, Choi Bum-Rak, Breitbach Martin, Doran Robert, Becher Ulrich M, Hwang Seong-Min, Bostani Toktam, von Maltzahn Julia, Hofmann Andreas, Reining Shaun, Eiberger Britta, Gabris Bethann, Pfeifer Alexander, Welz Armin, Willecke Klaus, Salama Guy, Schrickel Jan W, Kotlikoff Michael I, Fleischmann Bernd K, ;2007;Nature;450;819-24; 18064002
Homozygous fertilenot known
Homozygous viablenot known
Homozygous matings requirednot known
Immunocompromisednot known

Information from EMMA

Archiving centreCNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy

Literature references

  • Engraftment of connexin 43-expressing cells prevents post-infarct arrhythmia.;Roell Wilhelm, Lewalter Thorsten, Sasse Philipp, Tallini Yvonne N, Choi Bum-Rak, Breitbach Martin, Doran Robert, Becher Ulrich M, Hwang Seong-Min, Bostani Toktam, von Maltzahn Julia, Hofmann Andreas, Reining Shaun, Eiberger Britta, Gabris Bethann, Pfeifer Alexander, Welz Armin, Willecke Klaus, Salama Guy, Schrickel Jan W, Kotlikoff Michael I, Fleischmann Bernd K, ;2007;Nature;450;819-24; 18064002

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Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
For this strain no provider MTA is needed. Distribution is based on the EMMA conditions only.

EMMA conditions
Legally binding conditions for the transfer

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