MGI phenotypes (allele matching)
- abnormal cranium morphology / MGI
STOCK Tg(Col2a1-cre)1Bhr/H
| Status | Available to order |
| EMMA ID | EM:02518 |
| Citation information | RRID:IMSR_EM:02518 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | STOCK Tg(Col2a1-cre)1Bhr/H |
| Alternative name | Col2-Cre |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(Col2a1-cre)1Bhr |
| Gene/Transgene symbol | Tg(Col2a1-cre)1Bhr |
Information from provider
| Provider | Elizabeth Robertson |
| Provider affiliation | Sir William Dunn School of Pathology, University of Oxford |
| Additional owner | For further information contact Martin Fray, FESA Manager. m.fray@har.mrc.ac.uk |
| Genetic information | Transgenic strain expressing cre recombinase under control of collagen 2 promoter element. The cre recombinase is faithfully expressed in chondrocytes and can be used to delete gene function in developing bone or for activating genes regulated by cre recombinase. |
| Phenotypic information | No overt phenotype. |
| Breeding history | Outcrossed to CD1. |
| References |
|
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
MGI phenotypes (gene matching)
- abnormal cranium morphology / MGI
Literature references
- Col2a1-directed expression of Cre recombinase in differentiating chondrocytes in transgenic mice.;Ovchinnikov D A, Deng J M, Ogunrinu G, Behringer R R, ;2000;Genesis (New York, N.Y. : 2000);26;145-6; 10686612