MGI phenotypes (allele matching)
- abnormal cranium morphology / MGI
STOCK Tg(Col2a1-cre)1Bhr/H
| Status | Available to order |
| EMMA ID | EM:02518 |
| International strain name | STOCK Tg(Col2a1-cre)1Bhr/H |
| Alternative name | Col2-Cre |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(Col2a1-cre)1Bhr |
| Gene/Transgene symbol | Tg(Col2a1-cre)1Bhr |
Information from provider
| Provider | Elizabeth Robertson |
| Provider affiliation | Sir William Dunn School of Pathology, University of Oxford |
| Additional owner | For further information contact Martin Fray, FESA Manager. m.fray@har.mrc.ac.uk |
| Genetic information | Transgenic strain expressing cre recombinase under control of collagen 2 promoter element. The cre recombinase is faithfully expressed in chondrocytes and can be used to delete gene function in developing bone or for activating genes regulated by cre recombinase. |
| Phenotypic information | No overt phenotype. |
| Breeding history | Outcrossed to CD1. |
| References |
|
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
MGI phenotypes (gene matching)
- abnormal cranium morphology / MGI
Literature references
- Col2a1-directed expression of Cre recombinase in differentiating chondrocytes in transgenic mice.;Ovchinnikov D A, Deng J M, Ogunrinu G, Behringer R R, ;2000;Genesis (New York, N.Y. : 2000);26;145-6; 10686612