STOCK Tg(Prm-cre)58Og/H
| Status | Available to order |
| EMMA ID | EM:02517 |
| International strain name | STOCK Tg(Prm-cre)58Og/H |
| Alternative name | Pro Cre |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(Prm-cre)58Og |
| Gene/Transgene symbol | Tg(Prm-cre)58Og |
Information from provider
| Provider | Elizabeth Robertson |
| Provider affiliation | Sir William Dunn School of Pathology, University of Oxford |
| Additional owner | For further information contact Martin Fray, FESA Manager. m.fray@har.mrc.ac.uk |
| Genetic information | Transgenic strain in which protamine promoter sequences drive the expression of cre recombinase in developing sperm. When crossed to animals containing loxP flanked DNA sequences cre efficiently recombines and removes these sequences in the sperm. |
| Phenotypic information | No overt phenotype. |
| Breeding history | Outcrossed to CD1. |
| References |
|
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Literature references
- Protamine-Cre recombinase transgenes efficiently recombine target sequences in the male germ line of mice, but not in embryonic stem cells.;O'Gorman S, Dagenais N A, Qian M, Marchuk Y, ;1997;Proceedings of the National Academy of Sciences of the United States of America;94;14602-7; 9405659