STOCK Tg(APOA4)8021Feb/Cnrm
| Status | Available to order |
| EMMA ID | EM:00025 |
| Citation information | RRID:IMSR_EM:00025 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | STOCK Tg(APOA4)8021Feb/Cnrm |
| Alternative name | APOA4-Tg#8021 |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(APOA4)8021Feb |
| Gene/Transgene symbol | Tg(APOA4)8021Feb |
Information from provider
| Provider | Francisco E. Baralle |
| Provider affiliation | ICGEB-Inter.Centre Genetic Engineering Biotechnology |
| Genetic information | The human APOA4 gene was expressed under the control of the human APOA4 promoter. One copy of the transgene was inserted into the genome. |
| Phenotypic information | Human APOA4 protein was detected in plasma of mice carrying this transgene. Dyslipidemia and hypetriglyceridemia model, atherosclerosis model. |
| Breeding history | Crossed to CD1 then backcrossed to C57BL/6 (3-4 generations) |
| References |
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Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
| Animals used for archiving | homozygous C57BL/6J males, wild-type C57BL/6J females |
| Stage of embryos | 2-cell |
Literature references
- Regulation of the human apolipoprotein AIV gene expression in transgenic mice.;Baralle M, Vergnes L, Muro A F, Zakin M M, Baralle F E, Ochoa A, ;1999;FEBS letters;445;45-52; 10069372