IMPC phenotypes (allele matching)
129-Vimtm2Cba/Orl
| Status | Available to order |
| EMMA ID | EM:02410 |
| International strain name | 129-Vimtm2Cba/Orl |
| Alternative name | Vim2/Vim2 |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Vimtm2Cba, |
| Gene/Transgene symbol | Vim |
Information from provider
| Provider | Emma Colucci-Guyon |
| Provider affiliation | Institut Pasteur |
| Genetic information | Exon 1 of the vimentin gene is disrupted by insertion of a TK-neo expression cassette, which results in the inactivation of the gene. The TKneo expression cassette is kept in the mutated allele. |
| Phenotypic information | Mice devoid of vimentin develop and reproduce without any obvious defects. |
| References |
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Information from EMMA
| Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Pulverulent cataract / Orphanet_98984
Literature references
- Mice lacking vimentin develop and reproduce without an obvious phenotype.;Colucci-Guyon E, Portier M M, Dunia I, Paulin D, Pournin S, Babinet C, ;1994;Cell;79;679-94; 7954832