MGI phenotypes (allele matching)
B6.129S7-Del(16Cldn5-Hira)5Bld/Cnrm
| Status | Available to order |
| EMMA ID | EM:02405 |
| Citation information | RRID:IMSR_EM:02405 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6.129S7-Del(16Cldn5-Hira)5Bld/Cnrm |
| Alternative name | RV46 |
| Strain type | Targeted Mutant Strains : Other targeted |
| Allele/Transgene symbol | Del(16Cldn5-Hira)5Bld |
| Gene/Transgene symbol | Del(16Cldn5-Hira)5Bld |
Information from provider
| Provider | Antonio BALDINI |
| Provider affiliation | institute of biosciences and technologies, Texas A&M health science center |
| Genetic information | A targeting cassette containing a loxP site was inserted into intron 25 of the endogenous Hira gene in ES cells. A second loxP site was inserted by retroviral insertion into an intragenic region between Cdcrel1 and Cld5. A deletion of ~250kb was generated by cre recombination in ES cells. |
| Phenotypic information | None in heterozygotes. |
| Breeding history | Backcrossed to C57BL/6 inbred mice for 6 generations then maintained by breeding siblings. This breeding is required to maintain a behavioral phenotype. |
| References |
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Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Disease and phenotype information
Literature references
- Tbx1 haploinsufficieny in the DiGeorge syndrome region causes aortic arch defects in mice.;Lindsay E A, Vitelli F, Su H, Morishima M, Huynh T, Pramparo T, Jurecic V, Ogunrinu G, Sutherland H F, Scambler P J, Bradley A, Baldini A, ;2001;Nature;410;97-101; 11242049