B6N;D2-Tg(Ggt1-cre/ERT2)1Pepe/Cnrm

Status	Available to order
EMMA ID	EM:02393
Citation information	RRID:IMSR_EM:02393 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.
International strain name	B6N;D2-Tg(Ggt1-cre/ERT2)1Pepe/Cnrm
Alternative name	GGT::Cre-ER T2
Strain type	Transgenic Strains
Allele/Transgene symbol	Tg(Ggt1-cre/ERT2)1Pepe
Gene/Transgene symbol	Tg(Ggt1-cre/ERT2)1Pepe

Information from provider

Provider	Bernd Dworniczak
Provider affiliation	University Clinics Muenster
Additional owner	Dr. Petra Pennekamp, Institute of Human Genetics, Münster, Germany and Prof. Pierre Chambon, Institut Clinque de la Souris and IGBMC, Illkirch, France
Genetic information	Described in detail in: Dworniczak B, Skryabin B, Tchinda J, Heuck S, Seesing FJ, Metzger D, Chambon P, Horst J, Pennekamp P. Inducible Cre/loxP recombination in the mouse proximal tubule. Nephron Exp Nephrol. 2007;106(1):e11-20. Epub 2007 Mar 12.
Phenotypic information	None.
Breeding history	Founder animal was backcrossed to C57BL/6N. Transgenic animals were used as long as possible for breeding to minimize the chance of silencing of the transgene in advanced generations.
References	Inducible Cre/loxP recombination in the mouse proximal tubule.;Dworniczak Bernd, Skryabin Boris, Tchinda Joëlle, Heuck Silke, Seesing Franz-Josef, Metzger Daniel, Chambon Pierre, Horst Jürgen, Pennekamp Petra, ;2007;Nephron. Experimental nephrology;106;e11-20; 17356303

Information from EMMA

Archiving centre	CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy

Literature references

Inducible Cre/loxP recombination in the mouse proximal tubule.;Dworniczak Bernd, Skryabin Boris, Tchinda Joëlle, Heuck Silke, Seesing Franz-Josef, Metzger Daniel, Chambon Pierre, Horst Jürgen, Pennekamp Petra, ;2007;Nephron. Experimental nephrology;106;e11-20; 17356303
Low TGFβ1 expression prevents and high expression exacerbates diabetic nephropathy in mice.;Hathaway Catherine K, Gasim Adil M H, Grant Ruriko, Chang Albert S, Kim Hyung-Suk, Madden Victoria J, Bagnell C Robert, Jennette J Charles, Smithies Oliver, Kakoki Masao, ;2015;Proceedings of the National Academy of Sciences of the United States of America;112;5815-20; 25902541

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Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740^*
Rederivation of mice from frozen stock, delivery time available upon request . €3880^*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

^* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
For this strain no provider MTA is needed. Distribution is based on the EMMA conditions only.

EMMA conditions
Legally binding conditions for the transfer

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