MGI phenotypes (allele matching)
B6;129P2-Vipr1tm1Dgen/H
| Status | Available to order |
| EMMA ID | EM:02374 |
| International strain name | B6;129P2-Vipr1tm1Dgen/H |
| Alternative name | DELTAGEN_T673 |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Vipr1tm1Dgen |
| Gene/Transgene symbol | Vipr1 |
Information from provider
| Provider | Deltagen Inc. |
| Provider affiliation | Deltagen Inc. |
| Phenotypic information | Lethality: Some N0F2 mice did not survive to weaning age. Home cage observations: Movement: lack of coordination and hypoactivity, 34-54 day homozygous mice. Physical examination: Thin body habitus, hyperactive, ataxic, and/or abnormal gait in a 49 day homozygous mutant female and male, may have been related to genotype. Hunched body shape in two 300 day homozygous mutant females, may have been related to genotype. There were no significant differences detected in heterozygous mutant mice when compared with age- and gender-matched wild-type control mice. |
| References | None available |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
MGI phenotypes (gene matching)
- hypoglycemia / MGI
- gastrointestinal hemorrhage / MGI
- abnormal intestine morphology / MGI
- decreased body weight / MGI
- ataxia / MGI
- hypoactivity / MGI
- impaired coordination / MGI
- abnormal gait / MGI
- hunched posture / MGI
- postnatal growth retardation / MGI
- abnormal glucose homeostasis / MGI
- increased insulin sensitivity / MGI
- intestinal obstruction / MGI
- abnormal exocrine pancreas morphology / MGI
- impaired glucose tolerance / MGI
- abnormal enterocyte proliferation / MGI
- disorganized pancreatic islets / MGI
- enlarged cecum / MGI
- lethality at weaning, incomplete penetrance / MGI
- preweaning lethality, incomplete penetrance / MGI