B6;129P2-Pde8atm1Dgen/H

Status

Available to order

EMMA IDEM:02365
International strain nameB6;129P2-Pde8atm1Dgen/H
Alternative nameDELTAGEN_T853
Strain typeTargeted Mutant Strains : Knock-out
Allele/Transgene symbolPde8atm1Dgen
Gene/Transgene symbolPde8a

Information from provider

Provider Deltagen Inc.
Provider affiliationDeltagen Inc.
Phenotypic informationHomozygous mutants displayed a decreased response threshold to metrazol. Homozygous mutants displayed a decreased response threshold on the Hot Plate test.
ReferencesNone available

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

IMPC phenotypes (gene matching)
  • decreased lean body mass / IMPC
  • increased total body fat amount / IMPC
MGI phenotypes (allele matching)
  • abnormal enzyme/coenzyme activity / MGI
  • abnormal testosterone level / MGI
  • increased susceptibility to pharmacologically induced seizures / MGI
  • decreased thermal nociceptive threshold / MGI
MGI phenotypes (gene matching)
  • increased susceptibility to pharmacologically induced seizures / MGI
  • decreased thermal nociceptive threshold / MGI
  • abnormal enzyme/coenzyme activity / MGI
  • abnormal testosterone level / MGI

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*
  • Tissue - Types of tissue, service fee and delivery time available upon request

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

EMMA conditions
Legally binding conditions for the transfer

Other EMMA strains

Not found what you were looking for? Search here for other strains available from EMMA.


Search
INFRAFRONTIER® and European Mouse Mutant Archive - EMMA® are registered trademarks at the European Union Intellectual Property Office (EUIPO).