MGI phenotypes (allele matching)
B6;129P2-Pde4btm1Dgen/H
| Status | Available to order |
| EMMA ID | EM:02364 |
| International strain name | B6;129P2-Pde4btm1Dgen/H |
| Alternative name | DELTAGEN_T1169 |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Pde4btm1Dgen |
| Gene/Transgene symbol | Pde4b |
Information from provider
| Provider | Deltagen Inc. |
| Provider affiliation | Deltagen Inc. |
| Phenotypic information | Histopathology: Brain, cerebrum, vacuolization, homozygous females and males. Brain, cerebellum, vacuolization, homozygous females and males. Brain, brainstem, vacuolization, homozygous females and males. Spinal cord, vacuolization, homozygous females and males. |
| References | None available |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
| Animals used for archiving | heterozygous C57BL/6J |
Disease and phenotype information
MGI phenotypes (gene matching)
- abnormal spinal cord morphology / MGI
- decreased anxiety-related response / MGI
- increased exploration in new environment / MGI
- abnormal object recognition memory / MGI
- abnormal learning/memory/conditioning / MGI
- abnormal CNS synaptic transmission / MGI
- increased vertical activity / MGI
- decreased synaptic depression / MGI
- increased post-tetanic potentiation / MGI
- enhanced long term potentiation / MGI
- nervous system phenotype / MGI
- cardiovascular system phenotype / MGI
- behavior/neurological phenotype / MGI
- taste/olfaction phenotype / MGI
- brain vacuoles / MGI
- abnormal spatial working memory / MGI
- decreased tumor necrosis factor secretion / MGI
- impaired neutrophil recruitment / MGI
- impaired neutrophil chemotaxis / MGI
- impaired cued conditioning behavior / MGI
- decreased sensitivity to induced morbidity/mortality / MGI
- abnormal neuron differentiation / MGI
- enhanced learning / MGI