IMPC phenotypes (gene matching)
- abnormal retina morphology / IMPC
B6;129P2-Grm8tm1Dgen/H
| Status | Available to order |
| EMMA ID | EM:02360 |
| International strain name | B6;129P2-Grm8tm1Dgen/H |
| Alternative name | DELTAGEN_T657 |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Grm8tm1Dgen |
| Gene/Transgene symbol | Grm8 |
Information from provider
| Provider | Deltagen Inc. |
| Provider affiliation | Deltagen Inc. |
| Phenotypic information | Homozygous mutant animals displayed a statistically significant increase in total distance traveled in the open field test, relative to wild-type animals. Homozygous mutant animals displayed a statistically significant decrease in Prepulse Inhibition (PPI) with a 100dB prepulse. |
| References | None available |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
MGI phenotypes (gene matching)
- increased body weight / MGI
- increased anxiety-related response / MGI
- abnormal locomotor behavior / MGI
- decreased exploration in new environment / MGI
- impaired swimming / MGI
- insulin resistance / MGI
- increased percent body fat/body weight / MGI
- decreased physiological sensitivity to xenobiotic / MGI
- decreased prepulse inhibition / MGI