IMPC phenotypes (gene matching)
B6;129S5-Ddr1tm1Lex/Orl
| Status | Available to order |
| EMMA ID | EM:02343 |
| International strain name | B6;129S5-Ddr1tm1Lex/Orl |
| Alternative name | LEXKO-1928 |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Ddr1tm1Lex |
| Gene/Transgene symbol | Ddr1 |
Information from provider
| Provider | Lexicon Genetics, Inc. |
| Provider affiliation | Lexicon Pharmaceuticals |
| Phenotypic information | The homozygous mutant mice exhibited increased locomotor activity and a decreased anxiety-related response in the open field when compared with their wild-type littermates and the historical mean. |
| References | None available |
Information from EMMA
| Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
Disease and phenotype information
MGI phenotypes (gene matching)
- abnormal cranium morphology / MGI
- abnormal mammary gland development / MGI
- decreased anxiety-related response / MGI
- hyperactivity / MGI
- failure of embryo implantation / MGI
- postnatal growth retardation / MGI
- abnormal lactation / MGI
- abnormal outer ear morphology / MGI
- abnormal bone mineralization / MGI
- increased urine protein level / MGI
- renal/urinary system phenotype / MGI
- homeostasis/metabolism phenotype / MGI
- abnormal podocyte slit diaphragm morphology / MGI
- abnormal mammary gland duct morphology / MGI
- abnormal renal tubule epithelium morphology / MGI
- increased mammary gland epithelial cell proliferation / MGI
- increased renal glomerulus basement membrane thickness / MGI
- erythrocyturia / MGI
- abnormal aorta collagen fibril morphology / MGI