B6;129S5-Plekhm1Gt(OST201689)Lex/Orl

Status

Available to order

EMMA IDEM:02334
International strain nameB6;129S5-Plekhm1Gt(OST201689)Lex/Orl
Alternative nameLEXKO-0354
Strain typeGene-trap
Allele/Transgene symbolPlekhm1Gt(OST201689)Lex
Gene/Transgene symbolPlekhm1

Information from provider

Provider Lexicon Genetics, Inc.
Provider affiliationLexicon Pharmaceuticals
Phenotypic informationNo Notable Phenotype.
ReferencesNone available

Information from EMMA

Archiving centreInstitut de Transgenose, INTRAGENE, Orléans, France

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

IMPC phenotypes (gene matching)
  • decreased total body fat amount / IMPC
  • polycystic kidney / IMPC
  • decreased prepulse inhibition / IMPC
  • fibro-osseous lesion / IMPC
  • abnormal vertebrae morphology / IMPC
  • increased circulating alanine transaminase level / IMPC
  • abnormal optic disk morphology / IMPC
  • hyperplasia / IMPC
  • increased bone mineral density / IMPC
  • increased bone mineral content / IMPC
  • short tibia / IMPC
  • increased circulating aspartate transaminase level / IMPC
MGI phenotypes (gene matching)
  • abnormal osteoclast physiology / MGI
  • no abnormal phenotype detected / MGI
  • decreased lysosomal enzyme secretion / MGI
  • abnormal osteoclast morphology / MGI
  • decreased osteoblast cell number / MGI
  • decreased bone resorption / MGI
  • abnormal lysosome morphology / MGI
  • increased bone trabecula number / MGI
  • increased trabecular bone mass / MGI
  • increased trabecular bone volume / MGI
  • decreased bone trabecular spacing / MGI
  • decreased bone ossification / MGI
  • decreased bone mineralization / MGI

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
For this strain no provider MTA is needed. Distribution is based on the EMMA conditions only.

EMMA conditions
Legally binding conditions for the transfer

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