B6;129S5-Tpcn2tm1Lex/Orl

Status

Available to order

EMMA IDEM:02331
International strain nameB6;129S5-Tpcn2tm1Lex/Orl
Alternative nameLEXKO-845
Strain typeTargeted Mutant Strains : Knock-out
Allele/Transgene symbolTpcn2tm1Lex
Gene/Transgene symbolTpcn2

Information from provider

Provider Lexicon Genetics, Inc.
Provider affiliationLexicon Pharmaceuticals
Phenotypic informationNo notable phenotype was detected in the homozygous mutant mice. Disruption of the target gene was confirmed by Southern hybridization analysis.
ReferencesNone available

Information from EMMA

Archiving centreInstitut de Transgenose, INTRAGENE, Orléans, France

Disease and phenotype information

IMPC phenotypes (gene matching)
  • abnormal vocalization / IMPC
  • decreased circulating sodium level / IMPC
  • increased circulating triglyceride level / IMPC
  • abnormal behavior / IMPC
  • increased eosinophil cell number / IMPC
MGI phenotypes (gene matching)
  • no abnormal phenotype detected / MGI
  • no phenotypic analysis / MGI
  • abnormal pancreatic beta cell physiology / MGI

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
For this strain no provider MTA is needed. Distribution is based on the EMMA conditions only.

EMMA conditions
Legally binding conditions for the transfer

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