MGI phenotypes (allele matching)
B6;129S5-Senp2Gt(OST66117)Lex/Orl
| Status | Available to order |
| EMMA ID | EM:02328 |
| International strain name | B6;129S5-Senp2Gt(OST66117)Lex/Orl |
| Alternative name | LEXKO-678 |
| Strain type | Gene-trap |
| Allele/Transgene symbol | Senp2Gt(OST66117)Lex |
| Gene/Transgene symbol | Senp2 |
Information from provider
| Provider | Lexicon Genetics, Inc. |
| Provider affiliation | Lexicon Pharmaceuticals |
| Phenotypic information | Genetic data indicate that the mutation resulted in lethality to the homozygous mutants. Female heterozygous mice exhibited a slightly reduced non-fasting blood glucose level. Due to lethality, transcript expression analysis was not performed. |
| References | None available |
Information from EMMA
| Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
Disease and phenotype information
MGI phenotypes (gene matching)
- abnormal heart development / MGI
- abnormal atrioventricular cushion morphology / MGI
- convulsive seizures / MGI
- audiogenic seizures / MGI
- absent trophoblast giant cells / MGI
- premature death / MGI
- abnormal nervous system electrophysiology / MGI
- thin myocardium / MGI
- small placenta / MGI
- abnormal neuron physiology / MGI
- abnormal brain wave pattern / MGI
- abnormal trophoblast layer morphology / MGI
- abnormal trophoblast giant cell morphology / MGI
- pericardial effusion / MGI
- decreased circulating glucose level / MGI
- abnormal cardiac epithelial to mesenchymal transition / MGI
- atrioventricular block / MGI
- sinus bradycardia / MGI
- prenatal lethality, complete penetrance / MGI
- embryonic lethality during organogenesis, complete penetrance / MGI
- decreased spongiotrophoblast size / MGI