IMPC phenotypes (gene matching)
- preweaning lethality, complete penetrance / IMPC
B6;129S5-Senp1Gt(OST215108)Lex/Orl
| Status | Available to order |
| EMMA ID | EM:02327 |
| International strain name | B6;129S5-Senp1Gt(OST215108)Lex/Orl |
| Alternative name | LEXKO-1061 |
| Strain type | Gene-trap |
| Allele/Transgene symbol | Senp1Gt(OST215108)Lex |
| Gene/Transgene symbol | Senp1 |
Information from provider
| Provider | Lexicon Genetics, Inc. |
| Provider affiliation | Lexicon Pharmaceuticals |
| Phenotypic information | Genetic data indicate that the mutation resulted in lethality of the homozygous mutants. The heterozygous mice exhibited enhanced motor coordination during inverted screen testing when compared with their wild-type littermates. Due to lethality, transcript expression analysis was not performed. |
| References | None available |
Information from EMMA
| Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
Disease and phenotype information
MGI phenotypes (gene matching)
- abnormal erythropoiesis / MGI
- abnormal vascular development / MGI
- abnormal cell death / MGI
- small liver / MGI
- pale liver / MGI
- abnormal liver physiology / MGI
- anemia / MGI
- prenatal lethality / MGI
- abnormal megakaryocyte progenitor cell morphology / MGI
- decreased erythrocyte cell number / MGI
- no phenotypic analysis / MGI
- abnormal vitelline vasculature morphology / MGI
- decreased liver weight / MGI
- pallor / MGI
- enhanced coordination / MGI
- decreased fetal size / MGI
- hematopoietic system phenotype / MGI
- abnormal hemoglobin content / MGI
- abnormal granulocyte differentiation / MGI
- abnormal monocyte differentiation / MGI
- abnormal placental labyrinth vasculature morphology / MGI
- decreased erythroid progenitor cell number / MGI
- postnatal lethality, complete penetrance / MGI
- prenatal lethality, complete penetrance / MGI
- lethality throughout fetal growth and development, complete penetrance / MGI
- lethality throughout fetal growth and development, incomplete penetrance / MGI