MGI phenotypes (allele matching)
B6;129S5-Acsl3Gt(OST148301)Lex/Orl
| Status | Available to order |
| EMMA ID | EM:02308 |
| International strain name | B6;129S5-Acsl3Gt(OST148301)Lex/Orl |
| Alternative name | LEXKO-011 |
| Strain type | Gene-trap |
| Allele/Transgene symbol | Acsl3Gt(OST148301)Lex |
| Gene/Transgene symbol | Acsl3 |
Information from provider
| Provider | Lexicon Genetics, Inc. |
| Provider affiliation | Lexicon Pharmaceuticals |
| Phenotypic information | The homozygous mutant mice exhibited increased peripheral blood percentages of CD4 cells and decreased B cells when compared with their wild-type littermates and the historical means. Decreased IgG1 response to ovalbumin was noted in (-/-) mice. In addition, the male mutants exhibited signs of growth retardation, including decreased mean body weight and length, total tissue mass, and lean body mass. RT-PCR analysis revealed that the transcript was absent in the homozygous mutant mice. |
| References | None available |
Information from EMMA
| Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
Disease and phenotype information
MGI phenotypes (gene matching)