MGI phenotypes (allele matching)
B6;129S5-Acsl3Gt(OST148301)Lex/Orl
| Status | Available to order |
| EMMA ID | EM:02308 |
| Citation information | RRID:IMSR_EM:02308 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6;129S5-Acsl3Gt(OST148301)Lex/Orl |
| Alternative name | LEXKO-011 |
| Strain type | Gene-trap |
| Allele/Transgene symbol | Acsl3Gt(OST148301)Lex |
| Gene/Transgene symbol | Acsl3 |
Information from provider
| Provider | Lexicon Genetics, Inc. |
| Provider affiliation | Lexicon Pharmaceuticals |
| Phenotypic information | The homozygous mutant mice exhibited increased peripheral blood percentages of CD4 cells and decreased B cells when compared with their wild-type littermates and the historical means. Decreased IgG1 response to ovalbumin was noted in (-/-) mice. In addition, the male mutants exhibited signs of growth retardation, including decreased mean body weight and length, total tissue mass, and lean body mass. RT-PCR analysis revealed that the transcript was absent in the homozygous mutant mice. |
| References | None available |
Information from EMMA
| Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
Disease and phenotype information
MGI phenotypes (gene matching)