- abnormal lens morphology / IMPC
- cataract / IMPC
- abnormal pupil morphology / IMPC
- abnormal iris morphology / IMPC
- increased startle reflex / IMPC
- abnormal eye morphology / IMPC
- abnormal locomotor activation / IMPC
- increased B cell number / IMPC
- decreased T cell number / IMPC
- decreased CD8-positive, alpha-beta T cell number / IMPC
B6;129P2-Nr1d2tm1Dgen/H
Status | Available to order |
EMMA ID | EM:02304 |
International strain name | B6;129P2-Nr1d2tm1Dgen/H |
Alternative name | DELTAGEN_T407 |
Strain type | Targeted Mutant Strains : Knock-out |
Allele/Transgene symbol | Nr1d2tm1Dgen |
Gene/Transgene symbol | Nr1d2 |
Information from provider
Provider | Deltagen Inc. |
Provider affiliation | Deltagen Inc. |
Phenotypic information | Lethality: Few homozygous mutant mice were identified at weaning of the N0F2 generation. Weaned progeny from the heterozygous matings were genotyped. Few homozygous mutant mice were identified by PCR for the N0F2 generation, whereas wild-type and heterozygous mutant mice were identified. However, homozygous mutants were identified in the N1F2 generation. There were no significant differences detected in the homozygous or heterozygous mutant mice when compared with age- and gender-matched wild-type control mice. |
References | None available |
Information from EMMA
Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
MGI allele-associated human disease models
IMPC phenotypes (allele matching)
IMPC phenotypes (gene matching)
- abnormal iris morphology / IMPC
- abnormal locomotor activation / IMPC
- abnormal pupil morphology / IMPC
- increased circulating alanine transaminase level / IMPC
- abnormal lens morphology / IMPC
- increased B cell number / IMPC
- decreased T cell number / IMPC
- abnormal eye morphology / IMPC
- cataract / IMPC
- decreased CD8-positive, alpha-beta T cell number / IMPC
- increased startle reflex / IMPC
MGI phenotypes (allele matching)
MGI phenotypes (gene matching)
- abnormal heart morphology / MGI
- increased anxiety-related response / MGI
- no abnormal phenotype detected / MGI
- no phenotypic analysis / MGI
- impaired behavioral response to xenobiotic / MGI
- ostium primum atrial septal defect / MGI
- atrioventricular septal defect / MGI
- inlet ventricular septal defect / MGI
- common atrioventricular valve / MGI
- neonatal lethality, incomplete penetrance / MGI
- preweaning lethality, incomplete penetrance / MGI
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