B6;129P2-Pak2tm1Dgen/H

Status

Available to order

EMMA IDEM:02302
International strain nameB6;129P2-Pak2tm1Dgen/H
Alternative nameDELTAGEN_T3209
Strain typeTargeted Mutant Strains : Knock-out
Allele/Transgene symbolPak2tm1Dgen
Gene/Transgene symbolPak2

Information from provider

Provider Deltagen Inc.
Provider affiliationDeltagen Inc.
Phenotypic informationLethality: Homozygous mice were not identified at weaning. There were no significant differences detected in the heterozygous mutant mice when compared with age- and gender-matched wild-type control mice. Weaned progeny from the heterozygous matings were genotyped. No homozygous mutant mice were identified by PCR, whereas wild-type and heterozygous mutant mice were present. The genotypic ratio suggested either an embryonic or perinatal lethal phenotype.
ReferencesNone available

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

IMPC phenotypes (gene matching)
  • preweaning lethality, complete penetrance / IMPC
  • prolonged RR interval / IMPC
  • increased circulating amylase level / IMPC
  • increased mean corpuscular hemoglobin / IMPC
  • embryonic lethality prior to tooth bud stage / IMPC
  • increased mean corpuscular volume / IMPC
MGI phenotypes (allele matching)
  • preweaning lethality, complete penetrance / MGI
MGI phenotypes (gene matching)
  • abnormal cell death / MGI
  • open neural tube / MGI
  • decreased embryo size / MGI
  • embryonic growth retardation / MGI
  • impaired somite development / MGI
  • abnormal hematopoietic stem cell physiology / MGI
  • preweaning lethality, complete penetrance / MGI
  • increased fibroblast proliferation / MGI

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Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*
  • Tissue - Types of tissue, service fee and delivery time available upon request

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

EMMA conditions
Legally binding conditions for the transfer

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