B6;129P2-Npy6rtm1Dgen/H

Status

Available to order

EMMA IDEM:02300
International strain nameB6;129P2-Npy6rtm1Dgen/H
Alternative nameDELTAGEN_T639
Strain typeTargeted Mutant Strains : Knock-out
Allele/Transgene symbolNpy6rtm1Dgen
Gene/Transgene symbolNpy6r

Information from provider

Provider Deltagen Inc.
Provider affiliationDeltagen Inc.
Phenotypic informationHomozygous mutant mice displayed enhanced performance on the rotarod test when compared with age- and gender-matched wild-type control mice.
ReferencesNone available

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

MGI phenotypes (allele matching)
  • abnormal motor coordination/ balance / MGI
MGI phenotypes (gene matching)
  • increased brown adipose tissue amount / MGI
  • increased white adipose tissue amount / MGI
  • abnormal abdominal fat pad morphology / MGI
  • decreased body weight / MGI
  • decreased body size / MGI
  • hyperactivity / MGI
  • abnormal motor coordination/balance / MGI
  • decreased brown adipose tissue amount / MGI
  • increased circulating insulin level / MGI
  • hepatic steatosis / MGI
  • decreased circulating insulin level / MGI
  • increased liver weight / MGI
  • increased susceptibility to age related obesity / MGI
  • increased defecation amount / MGI
  • decreased lean body mass / MGI
  • abnormal circulating insulin-like growth factor I level / MGI
  • decreased circulating insulin-like growth factor I level / MGI
  • increased energy expenditure / MGI
  • improved glucose tolerance / MGI
  • impaired glucose tolerance / MGI
  • abnormal circulating corticosterone level / MGI
  • homeostasis/metabolism phenotype / MGI
  • reproductive system phenotype / MGI
  • abnormal food intake / MGI
  • abnormal energy expenditure / MGI
  • increased circulating glucose level / MGI
  • increased susceptibility to diet-induced obesity / MGI
  • increased epididymal fat pad weight / MGI
  • decreased epididymal fat pad weight / MGI
  • increased inguinal fat pad weight / MGI
  • decreased inguinal fat pad weight / MGI
  • decreased mesenteric fat pad weight / MGI
  • increased retroperitoneal fat pad weight / MGI
  • decreased retroperitoneal fat pad weight / MGI
  • increased total body fat amount / MGI
  • decreased total body fat amount / MGI
  • increased respiratory quotient / MGI
  • decreased respiratory quotient / MGI
  • increased food intake / MGI
  • decreased food intake / MGI
  • decreased defecation amount / MGI

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*
  • Tissue - Types of tissue, service fee and delivery time available upon request

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

EMMA conditions
Legally binding conditions for the transfer

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