MGI phenotypes (allele matching)
B6;129P2-Adgrg1tm1Dgen/H
| Status | Available to order |
| EMMA ID | EM:02297 |
| International strain name | B6;129P2-Adgrg1tm1Dgen/H |
| Alternative name | DELTAGEN_T963 |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Adgrg1tm1Dgen |
| Gene/Transgene symbol | Adgrg1 |
Information from provider
| Provider | Deltagen Inc. |
| Provider affiliation | Deltagen Inc. |
| Phenotypic information | Histopathology: Cerebellum, cortical malformation, homozygous mutants in 49 and 300 day cohorts. Behavior: Homozygous mutants displayed a higher average velocity than wild-types in the open field test. Behavior: Homozygous mutants displayed shorter response latencies in the hot plate test. There were no significant differences detected in the homozygous mutant animals when compared with age- and gender-matched wild-type control mice. |
| References |
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Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Bilateral perisylvian polymicrogyria / Orphanet_98889
- Bilateral frontoparietal polymicrogyria / Orphanet_101070
MGI phenotypes (gene matching)
Literature references
- International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors.;Hamann Jörg, Aust Gabriela, Araç Demet, Engel Felix B, Formstone Caroline, Fredriksson Robert, Hall Randy A, Harty Breanne L, Kirchhoff Christiane, Knapp Barbara, Krishnan Arunkumar, Liebscher Ines, Lin Hsi-Hsien, Martinelli David C, Monk Kelly R, Peeters Miriam C, Piao Xianhua, Prömel Simone, Schöneberg Torsten, Schwartz Thue W, Singer Kathleen, Stacey Martin, Ushkaryov Yuri A, Vallon Mario, Wolfrum Uwe, Wright Mathew W, Xu Lei, Langenhan Tobias, Schiöth Helgi B, ;2015;Pharmacological reviews;67;338-67; 25713288