B6;129P2-Adgrl4tm1Dgen/H

Status

Available to order

EMMA IDEM:02295
International strain nameB6;129P2-Adgrl4tm1Dgen/H
Alternative nameDELTAGEN_T1054
Strain typeTargeted Mutant Strains : Knock-out
Allele/Transgene symbolAdgrl4tm1Dgen
Gene/Transgene symbolAdgrl4

Information from provider

Provider Deltagen Inc.
Provider affiliationDeltagen Inc.
Phenotypic informationThere were no significant differences detected in the homozygous mutant mice when compared with age- and gender-matched wild-type control mice.
References
  • International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors.;Hamann Jörg, Aust Gabriela, Araç Demet, Engel Felix B, Formstone Caroline, Fredriksson Robert, Hall Randy A, Harty Breanne L, Kirchhoff Christiane, Knapp Barbara, Krishnan Arunkumar, Liebscher Ines, Lin Hsi-Hsien, Martinelli David C, Monk Kelly R, Peeters Miriam C, Piao Xianhua, Prömel Simone, Schöneberg Torsten, Schwartz Thue W, Singer Kathleen, Stacey Martin, Ushkaryov Yuri A, Vallon Mario, Wolfrum Uwe, Wright Mathew W, Xu Lei, Langenhan Tobias, Schiöth Helgi B, ;2015;Pharmacological reviews;67;338-67; 25713288

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

IMPC phenotypes (gene matching)
  • cataract / IMPC
  • eye hemorrhage / IMPC
  • decreased mean corpuscular volume / IMPC
  • small liver / IMPC
  • abnormal vitreous body morphology / IMPC
  • abnormal eye morphology / IMPC
  • abnormal liver morphology / IMPC
  • abnormal retina morphology / IMPC
  • decreased mean corpuscular hemoglobin / IMPC
  • abnormal skin morphology / IMPC
  • increased neutrophil cell number / IMPC
  • increased vertical activity / IMPC
MGI phenotypes (gene matching)
  • no abnormal phenotype detected / MGI

Literature references

  • International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors.;Hamann Jörg, Aust Gabriela, Araç Demet, Engel Felix B, Formstone Caroline, Fredriksson Robert, Hall Randy A, Harty Breanne L, Kirchhoff Christiane, Knapp Barbara, Krishnan Arunkumar, Liebscher Ines, Lin Hsi-Hsien, Martinelli David C, Monk Kelly R, Peeters Miriam C, Piao Xianhua, Prömel Simone, Schöneberg Torsten, Schwartz Thue W, Singer Kathleen, Stacey Martin, Ushkaryov Yuri A, Vallon Mario, Wolfrum Uwe, Wright Mathew W, Xu Lei, Langenhan Tobias, Schiöth Helgi B, ;2015;Pharmacological reviews;67;338-67; 25713288
  • Augmented cardiac hypertrophy in response to pressure overload in mice lacking ELTD1.;Xiao Jinfeng, Jiang Hong, Zhang Rui, Fan Guangpu, Zhang Yan, Jiang Dingsheng, Li Hongliang, ;2012;PloS one;7;e35779; 22606234

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*
  • Tissue - Types of tissue, service fee and delivery time available upon request

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

EMMA conditions
Legally binding conditions for the transfer

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