B6;129P2-Adamts1tm1Dgen/H

Status

Available to order

EMMA IDEM:02291
International strain nameB6;129P2-Adamts1tm1Dgen/H
Alternative nameDELTAGEN_T1228
Strain typeTargeted Mutant Strains : Knock-out
Allele/Transgene symbolAdamts1tm1Dgen
Gene/Transgene symbolAdamts1

Information from provider

Provider Deltagen Inc.
Provider affiliationDeltagen Inc.
Phenotypic informationNecropsy: Kidney enlarged and fluid-filled, 49 day homozygous mutant females and males. Weight and/or organ weight/body weight ratio increased, 49 day homozygous mutant females and males. Discolored, 49 day homozygous mutant male. Histopathology: Kidney Pelvis dilated, bilateral, 49 day homozygous females and males; unilateral, 49 day homozygous female. Cortex atrophic, 49 day homozygous females and males.
ReferencesNone available

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

IMPC phenotypes (gene matching)
  • abnormal tail morphology / IMPC
  • abnormal spleen morphology / IMPC
  • abnormal placenta vasculature / IMPC
  • no spontaneous movement / IMPC
  • abnormal placenta morphology / IMPC
  • abnormal kidney morphology / IMPC
  • abnormal blood vessel morphology / IMPC
  • eye hemorrhage / IMPC
  • abnormal body wall morphology / IMPC
  • small kidney / IMPC
  • preweaning lethality, incomplete penetrance / IMPC
  • enlarged spleen / IMPC
  • abnormal heart morphology / IMPC
  • small heart / IMPC
  • abnormal eye morphology / IMPC
MGI phenotypes (allele matching)
  • hydronephrosis / MGI
  • abnormal kidney morphology / MGI
  • enlarged kidney / MGI
  • increased kidney weight / MGI
  • kidney cortex atrophy / MGI
MGI phenotypes (gene matching)
  • hydronephrosis / MGI
  • abnormal ureter morphology / MGI
  • dilated uterus / MGI
  • decreased body weight / MGI
  • impaired embryo implantation / MGI
  • polyuria / MGI
  • reduced female fertility / MGI
  • decreased litter size / MGI
  • abnormal kidney morphology / MGI
  • decreased mature ovarian follicle number / MGI
  • enlarged kidney / MGI
  • decreased ovulation rate / MGI
  • ureter obstruction / MGI
  • increased kidney weight / MGI
  • homeostasis/metabolism phenotype / MGI
  • decreased urine potassium level / MGI
  • decreased urine sodium level / MGI
  • abnormal adrenal medulla morphology / MGI
  • uterus cysts / MGI
  • decreased total body fat amount / MGI
  • postnatal lethality, incomplete penetrance / MGI
  • perinatal lethality, incomplete penetrance / MGI
  • absent kidney papilla / MGI
  • dilated kidney calyx / MGI
  • abnormal kidney corticomedullary boundary morphology / MGI
  • kidney medulla atrophy / MGI
  • kidney cortex atrophy / MGI
  • decreased urine chloride ion level / MGI
  • abnormal ureteropelvic junction morphology / MGI
  • ureteropelvic junction obstruction / MGI
  • kidney papillary hypoplasia / MGI

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Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*
  • Tissue - Types of tissue, service fee and delivery time available upon request

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

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Legally binding conditions for the transfer

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