B6.Cg-Tg(Tagln-cre)1Zli/Orl
| Status | Available to order |
| EMMA ID | EM:02228 |
| International strain name | B6.Cg-Tg(Tagln-cre)1Zli/Orl |
| Alternative name | SM22-Cre |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(Tagln-cre)1Zli |
| Gene/Transgene symbol | Tg(Tagln-cre)1Zli |
Information from provider
| Provider | Zhenlin LI |
| Provider affiliation | Université Pierre et Marie Curie |
| Genetic information | The promoter of SM22 gene (from -2126 to +85) that has been characterized previously (Moessler H et al., Development 1996, 122:2415-25), was linked to the nls-cre recombinase from the beta MHC-Cre plasmid (Parlakian et al, Mol Cell Biol 2004, 24:5281-89). In the transgenic animals, promoter fragment directed cre recombinase expression initially in the heart and the somites of embryos and subsequently in the arteries of the vascular system, but in none of the visceral muscles, nor in the veins. |
| Phenotypic information | No observed defects. |
| References |
|
Information from EMMA
| Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
Literature references
- The SM 22 promoter directs tissue-specific expression in arterial but not in venous or visceral smooth muscle cells in transgenic mice.;Moessler H, Mericskay M, Li Z, Nagl S, Paulin D, Small J V, ;1996;Development (Cambridge, England);122;2415-25; 8756287