MGI phenotypes (allele matching)
B6.129S7-Del(16Es2el-T10)2Bld/Cnrm
| Status | Available to order |
| EMMA ID | EM:02202 |
| Citation information | RRID:IMSR_EM:02202 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6.129S7-Del(16Es2el-T10)2Bld/Cnrm |
| Alternative name | Df2 |
| Strain type | Targeted Mutant Strains : Other targeted |
| Allele/Transgene symbol | Del(16Es2el-T10)2Bld |
| Gene/Transgene symbol | Del(16Es2el-T10)2Bld |
Information from provider
| Provider | Antonio BALDINI |
| Provider affiliation | institute of biosciences and technologies, Texas A&M health science center |
| Genetic information | A loxP site was inserted into the gene Es2el by homologous recombination in ES cells. A second loxP site was inserted by retroviral transfection into the gene Txnrd2. Cre-induced recombination between the loxP sites generated a multi-gene deletion named Df2. |
| Phenotypic information | None in heterozygotes. |
| Breeding history | Backcrossed to C57BL/6 for 7 generations. |
| References |
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Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Disease and phenotype information
Literature references
- Tbx1 haploinsufficiency is linked to behavioral disorders in mice and humans: implications for 22q11 deletion syndrome.;Paylor Richard, Glaser Beate, Mupo Annalisa, Ataliotis Paris, Spencer Corinne, Sobotka Angela, Sparks Chelsey, Choi Chul-Hee, Oghalai John, Curran Sarah, Murphy Kieran C, Monks Stephen, Williams Nigel, O'Donovan Michael C, Owen Michael J, Scambler Peter J, Lindsay Elizabeth, ;2006;Proceedings of the National Academy of Sciences of the United States of America;103;7729-34; 16684884