B6.129S7-Del(16Es2el-T10)2Bld/Cnrm
Status | Available to order |
EMMA ID | EM:02202 |
International strain name | B6.129S7-Del(16Es2el-T10)2Bld/Cnrm |
Alternative name | Df2 |
Strain type | Targeted Mutant Strains : Other targeted |
Allele/Transgene symbol | Del(16Es2el-T10)2Bld |
Gene/Transgene symbol | Del(16Es2el-T10)2Bld |
Information from provider
Provider | Antonio BALDINI |
Provider affiliation | institute of biosciences and technologies, Texas A&M health science center |
Genetic information | A loxP site was inserted into the gene Es2el by homologous recombination in ES cells. A second loxP site was inserted by retroviral transfection into the gene Txnrd2. Cre-induced recombination between the loxP sites generated a multi-gene deletion named Df2. |
Phenotypic information | None in heterozygotes. |
Breeding history | Backcrossed to C57BL/6 for 7 generations. |
References |
|
Information from EMMA
Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Disease and phenotype information
Literature references
- Tbx1 haploinsufficiency is linked to behavioral disorders in mice and humans: implications for 22q11 deletion syndrome.;Paylor Richard, Glaser Beate, Mupo Annalisa, Ataliotis Paris, Spencer Corinne, Sobotka Angela, Sparks Chelsey, Choi Chul-Hee, Oghalai John, Curran Sarah, Murphy Kieran C, Monks Stephen, Williams Nigel, O'Donovan Michael C, Owen Michael J, Scambler Peter J, Lindsay Elizabeth, ;2006;Proceedings of the National Academy of Sciences of the United States of America;103;7729-34; 16684884
Information on how we integrate external resources can be found here
INFRAFRONTIER® and European Mouse Mutant Archive - EMMA® are registered trademarks at the European Union Intellectual Property Office (EUIPO).