| Status | Available to order |
| EMMA ID | EM:00022 |
| Citation information | RRID:IMSR_EM:00022 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6;SJL-Plekha5Tg(AMH-cre)1Flor/Orl |
| Alternative name | AMH-Cre |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Plekha5Tg(AMH-cre)1Flor |
| Gene/Transgene symbol | Plekha5 |
| Provider | Florian GUILLOU |
| Provider affiliation | INRA, INRA |
| Genetic information | A 3.6 Kbp EcoRI/AvrII fragment of the human anti-Mullerian hormone (AMH, or Mullerian inhibitor substance, MIS) gene promoter was inserted upstream of the cre recombinase gene with the metallothionein I polyadenylation signal. The cre gene contains a T to G transversion in the -3 position, relative to the AUG translation start, that increases the translational proficiency of the cre transcript. The insertion site of the original AMH-cre transgene has then been mapped to intron 3 of the Plekha5 gene. |
| Phenotypic information | This line has a scientific interest for conditional gene knock-out in Sertoli cells and granulosa cells. |
| Breeding history | 2 backcrosses to C57BL/6. |
| References |
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| Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
