STOCK Tg(ITGAM-PLA2G2A)1Winth/Cnrm

Status	Available to order
EMMA ID	EM:02189
International strain name	STOCK Tg(ITGAM-PLA2G2A)1Winth/Cnrm
Alternative name	sPLA2
Strain type	Transgenic Strains
Allele/Transgene symbol	Tg(ITGAM-PLA2G2A)1Winth
Gene/Transgene symbol	Tg(ITGAM-PLA2G2A)1Winth

Information from provider

Provider	Menno de Winther
Provider affiliation	Institute for Genetics, University of Cologne
Genetic information	Transgenic mice were generated using the human sPLA2 gene driven by the ITGAM (CD11b) promoter, leading to myeloid specific overexpression of human group IIa sPLA2.
Phenotypic information	Enhanced sPLA2 activity leading to increased atherosclerosis.
References	Macrophage-specific overexpression of group IIa sPLA2 increases atherosclerosis and enhances collagen deposition.;Ghesquiere Stijn A I, Gijbels Marion J J, Anthonsen Marit, van Gorp Patrick J J, van der Made Ingeborg, Johansen Berit, Hofker Marten H, de Winther Menno P J, ;2005;Journal of lipid research;46;201-10; 15576846

Information from EMMA

Archiving centre	CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy

Literature references

Macrophage-specific overexpression of group IIa sPLA2 increases atherosclerosis and enhances collagen deposition.;Ghesquiere Stijn A I, Gijbels Marion J J, Anthonsen Marit, van Gorp Patrick J J, van der Made Ingeborg, Johansen Berit, Hofker Marten H, de Winther Menno P J, ;2005;Journal of lipid research;46;201-10; 15576846

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740^*
Rederivation of mice from frozen stock, delivery time available upon request . €3880^*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

^* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
For this strain no provider MTA is needed. Distribution is based on the EMMA conditions only.

EMMA conditions
Legally binding conditions for the transfer

Other EMMA strains

Not found what you were looking for? Search here for other strains available from EMMA.