| Status | Available to order |
| EMMA ID | EM:02187 |
| Citation information | RRID:IMSR_EM:02187 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B(BR)-Steap3fred/ApbH |
| Alternative name | Redburst |
| Strain type | Induced Mutant Strains : Chemically-induced |
| Allele/Transgene symbol | Steap3fred |
| Gene/Transgene symbol | Steap3 |
| Provider | Chris Goodnow |
| Provider affiliation | The Australian National University |
| Genetic information | This mutation carries a point mutation T to C at nucleotide 862 (Y288H) and was identified during systematically screening of the mouse genome for autoimmune regulators. The mutation results in alteration in red blood cell development. A null mutant has been described which has defects in transferrin mediated iron uptake. |
| Phenotypic information | These mice carry abnormalities in red blood cell size and shape. |
| Breeding history | Original background: C57BL/6Apb. Maintained background: Mixed C57BL/6Apb x B10.BR. Breeding History: From G1 to G5 it was sib x sib mating on B6 background. Then male G5 was outcrossed to female B10.BR. Offspring were then mated sib x sib for two further generations. |
| References | None available |
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Orphanet associated rare diseases, based on orthologous gene matching
