B6.Cg-Tg(Pax8-rtTA2S*M2)1Koes/Ieg

Status	Available to order
EMMA ID	EM:02144
International strain name	B6.Cg-Tg(Pax8-rtTA2S*M2)1Koes/Ieg
Alternative name	Pax8rtTA
Strain type	Transgenic Strains
Allele/Transgene symbol	Tg(Pax8-rtTA2S*M2)1Koes
Gene/Transgene symbol	Tg(Pax8-rtTA2S*M2)1Koes

Information from provider

Provider	Robert Koesters
Provider affiliation	DKFZ
Genetic information	Recombinant rtTA-cDNA containing a consensus Kozak translational initiation site and a polyadenylation signal (AATAAA) was used to replace the endogenous Pax8 start codon (ATG) located within exon 2.
Phenotypic information	None.
Breeding history	5 generations C57BL/6 plus 1 generation inbred.
References	An efficient and versatile system for acute and chronic modulation of renal tubular function in transgenic mice.;Traykova-Brauch Milena, Schönig Kai, Greiner Oliver, Miloud Tewfik, Jauch Anna, Bode Manja, Felsher Dean W, Glick Adam B, Kwiatkowski David J, Bujard Hermann, Horst Jürgen, von Knebel Doeberitz Magnus, Niggli Felix K, Kriz Wilhelm, Gröne Hermann-Josef, Koesters Robert, ;2008;Nature medicine;14;979-84; 18724376

Information from EMMA

Archiving centre	Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany

Literature references

An efficient and versatile system for acute and chronic modulation of renal tubular function in transgenic mice.;Traykova-Brauch Milena, Schönig Kai, Greiner Oliver, Miloud Tewfik, Jauch Anna, Bode Manja, Felsher Dean W, Glick Adam B, Kwiatkowski David J, Bujard Hermann, Horst Jürgen, von Knebel Doeberitz Magnus, Niggli Felix K, Kriz Wilhelm, Gröne Hermann-Josef, Koesters Robert, ;2008;Nature medicine;14;979-84; 18724376

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Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Rederivation of mice from frozen stock, delivery time available upon request . €3880^*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

^* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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