B6.Cg-Tg(Pax8-rtTA2S*M2)1Koes/Ieg
| Status | Available to order |
| EMMA ID | EM:02144 |
| Citation information | RRID:IMSR_EM:02144 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6.Cg-Tg(Pax8-rtTA2S*M2)1Koes/Ieg |
| Alternative name | Pax8rtTA |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(Pax8-rtTA2S*M2)1Koes |
| Gene/Transgene symbol | Tg(Pax8-rtTA2S*M2)1Koes |
Information from provider
| Provider | Robert Koesters |
| Provider affiliation | DKFZ |
| Genetic information | Recombinant rtTA-cDNA containing a consensus Kozak translational initiation site and a polyadenylation signal (AATAAA) was used to replace the endogenous Pax8 start codon (ATG) located within exon 2. |
| Phenotypic information | None. |
| Breeding history | 5 generations C57BL/6 plus 1 generation inbred. |
| References |
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Information from EMMA
| Archiving centre | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany |
Literature references
- An efficient and versatile system for acute and chronic modulation of renal tubular function in transgenic mice.;Traykova-Brauch Milena, Schönig Kai, Greiner Oliver, Miloud Tewfik, Jauch Anna, Bode Manja, Felsher Dean W, Glick Adam B, Kwiatkowski David J, Bujard Hermann, Horst Jürgen, von Knebel Doeberitz Magnus, Niggli Felix K, Kriz Wilhelm, Gröne Hermann-Josef, Koesters Robert, ;2008;Nature medicine;14;979-84; 18724376