B6.FVB-Tg(Camk2a-cre/ERT2)2Gsc/Ieg
| Status | Available to order |
| EMMA ID | EM:02125 |
| International strain name | B6.FVB-Tg(Camk2a-cre/ERT2)2Gsc/Ieg |
| Alternative name | CaMKCreERT2 |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(Camk2a-cre/ERT2)2Gsc |
| Gene/Transgene symbol | Tg(Camk2a-cre/ERT2)2Gsc |
Information from provider
| Provider | Günther Schütz |
| Provider affiliation | Molecular Biology of the Cell I, German Cancer Research Center |
| Genetic information | cre/ERT2 (or CreESR1; tamoxifen-inducible) recombinase placed under control of the mouse Camk2a (CaMKIIalpha) gene regulatory elements in a BAC vector. |
| Phenotypic information | None. |
| References |
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Information from EMMA
| Archiving centre | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany |
| Animals used for archiving | heterozygous C57BL/6N |
Literature references
- Inducible gene inactivation in neurons of the adult mouse forebrain.;Erdmann Gitta, Schütz Günther, Berger Stefan, ;2007;BMC neuroscience;8;63; 17683525
- Neuronal expression of glucosylceramide synthase in central nervous system regulates body weight and energy homeostasis.;Nordström Viola, Willershäuser Monja, Herzer Silke, Rozman Jan, von Bohlen Und Halbach Oliver, Meldner Sascha, Rothermel Ulrike, Kaden Sylvia, Roth Fabian C, Waldeck Clemens, Gretz Norbert, de Angelis Martin Hrabě, Draguhn Andreas, Klingenspor Martin, Gröne Hermann-Josef, Jennemann Richard, ;2013;PLoS biology;11;e1001506; 23554574
- Prox1 postmitotically defines dentate gyrus cells by specifying granule cell identity over CA3 pyramidal cell fate in the hippocampus.;Iwano Tomohiko, Masuda Aki, Kiyonari Hiroshi, Enomoto Hideki, Matsuzaki Fumio, ;2012;Development (Cambridge, England);139;3051-62; 22791897
- A Critical Role of Presynaptic Cadherin/Catenin/p140Cap Complexes in Stabilizing Spines and Functional Synapses in the Neocortex.;Li Min-Yin, Miao Wan-Ying, Wu Qiu-Zi, He Shun-Ji, Yan Guoquan, Yang Yanrui, Liu Jia-Jia, Taketo M Mark, Yu Xiang, ;2017;Neuron;94;1155-1172.e8; 28641114
- Adult Deletion of SRF Increases Epileptogenesis and Decreases Activity-Induced Gene Expression.;Kuzniewska Bozena, Nader Karolina, Dabrowski Michal, Kaczmarek Leszek, Kalita Katarzyna, ;2016;Molecular neurobiology;53;1478-1493; 25636686
- Sonic hedgehog is a regulator of extracellular glutamate levels and epilepsy.;Feng Shengjie, Ma Shaorong, Jia Caixia, Su Yujuan, Yang Shenglian, Zhou Kechun, Liu Yani, Cheng Ju, Lu Dunguo, Fan Liu, Wang Yizheng, ;2016;EMBO reports;17;682-94; 27113760
- Huntingtin acts non cell-autonomously on hippocampal neurogenesis and controls anxiety-related behaviors in adult mouse.;Pla Patrick, Orvoen Sophie, Benstaali Caroline, Dodier Sophie, Gardier Alain M, David Denis J, Humbert Sandrine, Saudou Frédéric, ;2013;PloS one;8;e73902; 24019939
- Synaptic dysfunction, memory deficits and hippocampal atrophy due to ablation of mitochondrial fission in adult forebrain neurons.;Oettinghaus B, Schulz J M, Restelli L M, Licci M, Savoia C, Schmidt A, Schmitt K, Grimm A, Morè L, Hench J, Tolnay M, Eckert A, D'Adamo P, Franken P, Ishihara N, Mihara K, Bischofberger J, Scorrano L, Frank S, ;2016;Cell death and differentiation;23;18-28; 25909888
- Clock-Controlled Mitochondrial Dynamics Correlates with Cyclic Pregnenolone Synthesis.;Witzig Melissa, Grimm Amandine, Schmitt Karen, Lejri Imane, Frank Stephan, Brown Steven A, Eckert Anne, ;2020;Cells;9;; 33086741