B6;129S7-Dp(16Dgcr14-Ufd1l)217Bld/Cnrm
| Status | Available to order |
| EMMA ID | EM:02121 |
| Citation information | RRID:IMSR_EM:02121 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6;129S7-Dp(16Dgcr14-Ufd1l)217Bld/Cnrm |
| Alternative name | Dp(16)1_Bld |
| Strain type | Targeted Mutant Strains : Other targeted |
| Allele/Transgene symbol | Dp(16Dgcr14-Ufd1l)217Bld |
| Gene/Transgene symbol | Dp(16Dgcr14-Ufd1l)217Bld |
Information from provider
| Provider | Antonio BALDINI |
| Provider affiliation | Institute of Genetics and Biophysics (IGB), National Research Council (CNR) |
| Genetic information | LoxP sites were inserted in trans into genes Es2 and Ufd1l; cre recombination in ES cells generated a chromosomal deletion named Df(16)1_Bld, and a chromosomal duplication named Dp(16)1_Bld. The two mutations were independently established in mice. |
| Phenotypic information | There are no overt phenotypic abnormalities associated with this duplication, except for behavioral abnormalities (hyperactivity) not yet fully characterized. |
| Breeding history | Backcrossed to C57BL/6 and then intercrossed; mixed 129 and C57BL/6 (ca. 75% C57BL/6) background. |
| References |
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Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Literature references
- Congenital heart disease in mice deficient for the DiGeorge syndrome region.;Lindsay E A, Botta A, Jurecic V, Carattini-Rivera S, Cheah Y C, Rosenblatt H M, Bradley A, Baldini A, ;1999;Nature;401;379-83; 10517636