CByIco.Cg-Tg(DO11.10)10Dlo/Cnrm

Status	Available to order
EMMA ID	EM:02105
International strain name	CByIco.Cg-Tg(DO11.10)10Dlo/Cnrm
Alternative name	BALB/cByJIco DO11.10
Strain type	Transgenic Strains
Allele/Transgene symbol	Tg(DO11.10)10Dlo
Gene/Transgene symbol	Tg(DO11.10)10Dlo

Information from provider

Provider	Ursula Günthert
Provider affiliation	Institut für Pathologie, University of Basel
Genetic information	The DO11.10 transgenic line was generated by oocyte injection of a cDNA encoding the T cell receptor DO11.10, reactive to the chicken ovalbumin peptide 323-339. The BALB/cByJIco DO11.10 mice are the reference mice for BALB/cByJIco DO11.10 CD44v6v7-/- and DO11.10 CD44v7-/-.
Phenotypic information	DO11.10: Expresses transgenic TCR that recognizes chicken ovalbumin in the context of I-Ad (class II restricted).
Breeding history	Backcrossed for 10 generations onto BALB/cByJIco.
References	Induction by antigen of intrathymic apoptosis of CD4+CD8+TCRlo thymocytes in vivo.;Murphy K M, Heimberger A B, Loh D Y, ;1990;Science (New York, N.Y.);250;1720-3; 2125367

Information from EMMA

Archiving centre	CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy

Literature references

Induction by antigen of intrathymic apoptosis of CD4+CD8+TCRlo thymocytes in vivo.;Murphy K M, Heimberger A B, Loh D Y, ;1990;Science (New York, N.Y.);250;1720-3; 2125367

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Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740^*
Rederivation of mice from frozen stock, delivery time available upon request . €3880^*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

^* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
For this strain no provider MTA is needed. Distribution is based on the EMMA conditions only.

EMMA conditions
Legally binding conditions for the transfer

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