CByIco.Cg-Tg(DO11.10)10Dlo/Cnrm
| Status | Available to order |
| EMMA ID | EM:02105 |
| Citation information | RRID:IMSR_EM:02105 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | CByIco.Cg-Tg(DO11.10)10Dlo/Cnrm |
| Alternative name | BALB/cByJIco DO11.10 |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(DO11.10)10Dlo |
| Gene/Transgene symbol | Tg(DO11.10)10Dlo |
Information from provider
| Provider | Ursula Günthert |
| Provider affiliation | Institut für Pathologie, University of Basel |
| Genetic information | The DO11.10 transgenic line was generated by oocyte injection of a cDNA encoding the T cell receptor DO11.10, reactive to the chicken ovalbumin peptide 323-339. The BALB/cByJIco DO11.10 mice are the reference mice for BALB/cByJIco DO11.10 CD44v6v7-/- and DO11.10 CD44v7-/-. |
| Phenotypic information | DO11.10: Expresses transgenic TCR that recognizes chicken ovalbumin in the context of I-Ad (class II restricted). |
| Breeding history | Backcrossed for 10 generations onto BALB/cByJIco. |
| References |
|
Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Literature references
- Induction by antigen of intrathymic apoptosis of CD4+CD8+TCRlo thymocytes in vivo.;Murphy K M, Heimberger A B, Loh D Y, ;1990;Science (New York, N.Y.);250;1720-3; 2125367