C.B-H2b/Orl

Status

Available to order

EMMA IDEM:00210
Citation informationRRID:IMSR_EM:00210 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

 
International strain nameC.B-H2b/Orl
Alternative nameBALB/c.B-H2b/Cdta
Strain typeOther
Allele/Transgene symbolH2b
Gene/Transgene symbolH2

Information from provider

ProviderCDTA unknown
Provider affiliationCNRS-Orleans
Phenotypic informationThe BALB/c.b mouse strain has a BALB/c genetic background but carries a different allele (H2b) derived from the BALB/c.B/Orl strain. The congenic mice are sensitive to increased immunodeficiency produced by murine leukemia viruses.
References
  • Rapid development of murine AIDS is dependent of signals provided by CD54 and CD11a.;Makino M, Yoshimatsu K, Azuma M, Okada Y, Hitoshi Y, Yagita H, Takatsu K, Komuro K, ;1995;Journal of immunology (Baltimore, Md. : 1950);155;974-81; 7608573

Information from EMMA

Archiving centreInstitut de Transgenose, INTRAGENE, Orléans, France

Disease and phenotype information

MGI phenotypes (allele matching)
  • decreased susceptibility to autoimmune diabetes / MGI
  • periinsulitis / MGI
  • decreased physiological sensitivity to xenobiotic / MGI
  • decreased hematocrit / MGI
  • abnormal liver physiology / MGI
  • abnormal T cell differentiation / MGI
  • abnormal cytokine secretion / MGI
  • increased autoantibody level / MGI
  • decreased susceptibility to parasitic infection / MGI
MGI phenotypes (gene matching)
  • decreased hematocrit / MGI
  • abnormal liver physiology / MGI
  • abnormal T cell differentiation / MGI
  • increased susceptibility to bacterial infection / MGI
  • abnormal immunoglobulin level / MGI
  • increased IgM level / MGI
  • abnormal cytokine secretion / MGI
  • thyroid inflammation / MGI
  • increased autoantibody level / MGI
  • insulitis / MGI
  • increased susceptibility to autoimmune diabetes / MGI
  • decreased susceptibility to autoimmune diabetes / MGI
  • decreased susceptibility to parasitic infection / MGI
  • immune system phenotype / MGI
  • periinsulitis / MGI
  • abnormal T cell number / MGI
  • decreased CD4-positive, alpha beta T cell number / MGI
  • increased CD8-positive, alpha-beta T cell number / MGI
  • decreased IgG1 level / MGI
  • decreased IgG2a level / MGI
  • increased physiological sensitivity to xenobiotic / MGI
  • decreased physiological sensitivity to xenobiotic / MGI
  • increased sensitivity to induced morbidity/mortality / MGI

Literature references

  • Rapid development of murine AIDS is dependent of signals provided by CD54 and CD11a.;Makino M, Yoshimatsu K, Azuma M, Okada Y, Hitoshi Y, Yagita H, Takatsu K, Komuro K, ;1995;Journal of immunology (Baltimore, Md. : 1950);155;974-81; 7608573

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Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

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Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
For this strain no provider MTA is needed. Distribution is based on the EMMA conditions only.

EMMA conditions
Legally binding conditions for the transfer

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