MGI phenotypes (allele matching)
- behavior/neurological phenotype / MGI
B6;129P2-Del(10Prmt2-Cstb)4Yah/Orl
| Status | Available to order |
| EMMA ID | EM:02099 |
| Citation information | RRID:IMSR_EM:02099 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6;129P2-Del(10Prmt2-Cstb)4Yah/Orl |
| Alternative name | Del(Prmt2-Cstb)Ms4Yah |
| Strain type | Targeted Mutant Strains : Other targeted |
| Allele/Transgene symbol | Del(10Prmt2-Cstb)4Yah |
| Gene/Transgene symbol | Del(10Prmt2-Cstb)4Yah |
Information from provider
| Provider | Yann HERAULT |
| Provider affiliation | TAAM-CDTA UPS44, Institut de Transgenose, INTRAGENE |
| Genetic information | Deletion of the region between the Prmt2 (synonym=Hrmt1l1) and Cstb genes engineered using MICER in ES (HM-1) cells. |
| Phenotypic information | Homozygotes: early embryonic lethal. Heterozygotes: no major defects. |
| References |
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Information from EMMA
| Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
Disease and phenotype information
MGI phenotypes (gene matching)
- behavior/neurological phenotype / MGI
Literature references
- The telomeric part of the human chromosome 21 from Cstb to Prmt2 is not necessary for the locomotor and short-term memory deficits observed in the Tc1 mouse model of Down syndrome.;Duchon Arnaud, Pothion Stéphanie, Brault Véronique, Sharp Andrew J, Tybulewicz Victor L J, Fisher Elizabeth M C, Herault Yann, ;2011;Behavioural brain research;217;271-81; 21047530
- Rodent models in Down syndrome research: impact and future opportunities.;Herault Yann, Delabar Jean M, Fisher Elizabeth M C, Tybulewicz Victor L J, Yu Eugene, Brault Veronique, ;2017;Disease models & mechanisms;10;1165-1186; 28993310