IMPC phenotypes (gene matching)
B6.129S7-Pof1btm1Toni/Cnrm
| Status | Available to order |
| EMMA ID | EM:02072 |
| Citation information | RRID:IMSR_EM:02072 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6.129S7-Pof1btm1Toni/Cnrm |
| Alternative name | Pofib3b6/1h11 |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Pof1btm1Toni |
| Gene/Transgene symbol | Pof1b |
Information from provider
| Provider | Daniela Toniolo |
| Provider affiliation | San Raffaele Scientific Institute |
| Genetic information | Insertion of the lacZ-neo cassette in the StuI site of first exon of Pof1b gene, 192 bp from the ATG. |
| Phenotypic information | No defects could be detected. |
| Breeding history | Mice were backcrossed for 7 generations to C57BL/6. |
| References |
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Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Disease and phenotype information
MGI phenotypes (gene matching)
- no abnormal phenotype detected / MGI
Literature references
- Mutation analysis of two candidate genes for premature ovarian failure, DACH2 and POF1B.;Bione S, Rizzolio F, Sala C, Ricotti R, Goegan M, Manzini M C, Battaglia R, Marozzi A, Vegetti W, Dalprà L, Crosignani P G, Ginelli E, Nappi R, Bernabini S, Bruni V, Torricelli F, Zuffardi O, Toniolo D, ;2004;Human reproduction (Oxford, England);19;2759-66; 15459172
- Disruption of POF1B binding to nonmuscle actin filaments is associated with premature ovarian failure.;Lacombe Arnaud, Lee Hane, Zahed Laila, Choucair Mahmoud, Muller Jean-Marc, Nelson Stanley F, Salameh Wael, Vilain Eric, ;2006;American journal of human genetics;79;113-9; 16773570